蛋白质-蛋白质相互作用网络模型的比较研究

2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops Pub Date : 2012-10-04 DOI:10.1109/BIBM.2012.6392732

Mingyu Shao, Yi Yang, J. Guan, Shuigeng Zhou

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引用次数: 1

摘要

本文通过比较原始PPI网络和模型复制网络的全局和局部统计特性，对现有主要模型在两个PPI数据集上的性能进行了全面的比较研究。实验结果表明，DD模型具有最佳的拟合能力，而iSite模型和STICKY模型对PPI数据集的大部分统计属性也具有较好的拟合能力。

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A comparison study on protein-protein interaction network models

This paper presents a comprehensive comparison study on the performances of major existing models over two PPI datasets, by comparing the global and local statistical properties of the original PPI networks and the model-reproduced ones. Our experimental results show that the DD model has best fitting ability while iSite model and STICKY model also fit well with the PPI datasets over most statistical properties.

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2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops

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