血铅水平与儿童贫血的关系

A. Pradhan, C. Aundhakar, M. Karguppikar
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引用次数: 1

摘要

背景:铅污染是发展中国家的一个主要问题。儿童铅接触是影响儿童的最严重的环境健康威胁之一。在儿童中,它被定义为血铅水平等于或大于10微克/分升。缺铁是导致低色性小细胞贫血的原因,也会增加对铅等元素的吸收。儿童贫血导致发病率和死亡率增加。这项研究是为了确定血铅水平大于10微克/分升与低于10微克/分升与贫血的关系。材料与方法:对100名儿童进行前瞻性观察研究。对每个儿童进行血红蛋白、MCV、RDW和血铅水平检测。50名患有贫血症的儿童和同等数量的没有贫血症的儿童参加了这项研究,并对他们的血铅水平进行了分析和测试。结果:100例患儿中,男63例,女37例。患儿总体平均年龄73.65 + 52.94个月,男性平均年龄73.30 + 51.52个月,女性平均年龄74.24 + 55.99个月。MCV缺铁性贫血患病率为64.2%,RDW缺铁性贫血患病率为58.8%。结论:MCV和RDW对缺铁性贫血的患病率分别为64.2%和58.8%。然而,贫血组和非贫血组在MCV和RDW方面存在显著差异。根据这项研究,该地区的铅接触很少,也没有铅毒性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relation between Blood Lead Levels and Childhood Anemia
Background: Lead pollution is a major problem in developing countries. Childhood lead exposure is one of the most significant environmental health threats that affects children. In children, it is defined as a blood lead level equal to or greater than 10 µg/dl. Iron deficiency is a cause of hypochromic microcytic anemia, and also increases the absorption of elements like lead. Anemia in children leads to increased morbidity and mortality. This study was done to determine the relation of blood lead levels greater than 10 µg/dl with the anemia compared to levels less than 10 µg/dl. Material and methods: The conduct prospective observational study was conducted on 100 children. For each children haemoglobin, MCV, RDW and blood lead level were tested. 50 children with proven anemia and equal number of children without anemia were enrolled in the study and was analysed and their blood lead levels were tested. Results: Out of 100 children, 63 were male and 37 were female. The overall children mean age was 73.65 + 52.94 months, male mean age was 73.30 + 51.52 months & female mean age was 74.24 + 55.99 months. The Prevalence of Iron Deficiency Anemia by MCV is 64.2% and Prevalence of Iron Deficiency Anemia by RDW is 58.8%. Conclusion: Prevalence of Iron Deficiency anemia by MCV and RDW was 64.2% and 58.8%. However there was a significant difference between the anemic and Non anemic group regarding MCV and RDW. According to the study, there is minimal lead exposure and no lead toxicity in this area.
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