耐辐射球菌的电离辐射抗性

Wei Li, Yun Ma, Fangzhu Xiao, Shu-ya He
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引用次数: 2

摘要

耐辐射球菌在抵抗电离辐射和其他dna损伤因素的能力方面是所有已知物种中无与伦比的。它被认为是研究DNA损伤和修复的模式生物。用急性剂量5000戈瑞的电离辐射治疗耐辐射曲菌,几乎不丧失生存能力,急性剂量15000戈瑞,37%的生存能力。这种细菌具有极强的抗辐射能力是由于其高效的DNA修复能力、高抗氧化活性和独特的细胞结构。本文根据最新研究成果,综述了耐辐射菌的一般特性及其抗电离辐射机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ionizing Radiation Resistance in Deinococcus Radiodurans
Deinococcus radiodurans is unmatched among all known species in its ability to resist ionizing radiation and other DNA-damaging factors. It is considered a model organism in the study of DNA damage and repair. Treatment of D. radiodurans with an acute dose of 5,000 Gy of ionizing radiation with almost no loss of viability, and an acute dose of 15,000 Gy with 37% viability. The extreme radiation resistance of this bacterium is due to efficient DNA repair capacity, high antioxidant activities, and unique cell structure. Based on the latest findings, the general characteristics and ionizing radiation resistance mechanisms of D. radiodurans are reviewed and discussed in this paper.
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