脂蛋白检测:改进特征集的混合深度分类模型

IF 0.6 Q4 COMPUTER SCIENCE, THEORY & METHODS
P. N. Kathavate, J. Amudhavel
{"title":"脂蛋白检测:改进特征集的混合深度分类模型","authors":"P. N. Kathavate, J. Amudhavel","doi":"10.3233/mgs-220329","DOIUrl":null,"url":null,"abstract":"Patients with chronic liver diseases typically experience lipid profile problems, and mortality from cirrhosis complicated by portal vein thrombosis (PVT) is very significant. A lipoprotein (Lp) is a bio-chemical assemblage with the main job of moving fat molecules in water that are hydrophobic. Lipoproteins are present in all eubacterial walls. Lipoproteins are of tremendous interest in the study of spirochaetes’ pathogenic mechanisms. Since spirochaete lipobox sequences are more malleable than other bacteria, it’s proven difficult to apply current prediction methods to new sequence data. The major goal is to present a Lipoprotein detection model in which correlation features, enhanced log energy entropy, raw features, and semantic similarity features are extracted. These extracted characteristics are put through a hybrid model that combines a Gated Recurrent Unit (GRU) and a Long Short-Term Memory (LSTM). Then, the outputs of GRU and LSTM are averaged to obtain the output. Here, GRU weights are optimized via the Selfish combined Henry Gas Solubility Optimization with cubic map initialization (SHGSO) model.","PeriodicalId":43659,"journal":{"name":"Multiagent and Grid Systems","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2023-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lipoprotein detection: Hybrid deep classification model with improved feature set\",\"authors\":\"P. N. Kathavate, J. Amudhavel\",\"doi\":\"10.3233/mgs-220329\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Patients with chronic liver diseases typically experience lipid profile problems, and mortality from cirrhosis complicated by portal vein thrombosis (PVT) is very significant. A lipoprotein (Lp) is a bio-chemical assemblage with the main job of moving fat molecules in water that are hydrophobic. Lipoproteins are present in all eubacterial walls. Lipoproteins are of tremendous interest in the study of spirochaetes’ pathogenic mechanisms. Since spirochaete lipobox sequences are more malleable than other bacteria, it’s proven difficult to apply current prediction methods to new sequence data. The major goal is to present a Lipoprotein detection model in which correlation features, enhanced log energy entropy, raw features, and semantic similarity features are extracted. These extracted characteristics are put through a hybrid model that combines a Gated Recurrent Unit (GRU) and a Long Short-Term Memory (LSTM). Then, the outputs of GRU and LSTM are averaged to obtain the output. Here, GRU weights are optimized via the Selfish combined Henry Gas Solubility Optimization with cubic map initialization (SHGSO) model.\",\"PeriodicalId\":43659,\"journal\":{\"name\":\"Multiagent and Grid Systems\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2023-02-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Multiagent and Grid Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3233/mgs-220329\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"COMPUTER SCIENCE, THEORY & METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Multiagent and Grid Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3233/mgs-220329","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"COMPUTER SCIENCE, THEORY & METHODS","Score":null,"Total":0}
引用次数: 0

摘要

慢性肝病患者通常会出现血脂问题,肝硬化并发门静脉血栓(PVT)的死亡率非常高。脂蛋白(Lp)是一种生物化学组合物,其主要工作是在水中移动疏水的脂肪分子。脂蛋白存在于所有真细菌的细胞壁中。脂蛋白在螺旋体致病机制的研究中具有重要意义。由于螺旋体脂盒序列比其他细菌更具延展性,因此很难将现有的预测方法应用于新的序列数据。主要目标是提出一种脂蛋白检测模型,其中提取了相关特征、增强的对数能量熵、原始特征和语义相似特征。这些提取的特征通过门控循环单元(GRU)和长短期记忆(LSTM)相结合的混合模型进行处理。然后,对GRU和LSTM的输出进行平均,得到输出。在这里,GRU的权重是通过自私的Henry气体溶解度优化和立方映射初始化(SHGSO)模型来优化的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lipoprotein detection: Hybrid deep classification model with improved feature set
Patients with chronic liver diseases typically experience lipid profile problems, and mortality from cirrhosis complicated by portal vein thrombosis (PVT) is very significant. A lipoprotein (Lp) is a bio-chemical assemblage with the main job of moving fat molecules in water that are hydrophobic. Lipoproteins are present in all eubacterial walls. Lipoproteins are of tremendous interest in the study of spirochaetes’ pathogenic mechanisms. Since spirochaete lipobox sequences are more malleable than other bacteria, it’s proven difficult to apply current prediction methods to new sequence data. The major goal is to present a Lipoprotein detection model in which correlation features, enhanced log energy entropy, raw features, and semantic similarity features are extracted. These extracted characteristics are put through a hybrid model that combines a Gated Recurrent Unit (GRU) and a Long Short-Term Memory (LSTM). Then, the outputs of GRU and LSTM are averaged to obtain the output. Here, GRU weights are optimized via the Selfish combined Henry Gas Solubility Optimization with cubic map initialization (SHGSO) model.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Multiagent and Grid Systems
Multiagent and Grid Systems COMPUTER SCIENCE, THEORY & METHODS-
CiteScore
1.50
自引率
0.00%
发文量
13
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信