Registro Nacional de Actividad – Registro de la Sociedad Española de Fertilidad de fecundación in vitro e inyección espermática intracitoplasmática: años 2018 y 2019

Introduction

This document presents the IVF/ICSI activity records of the National Activity Register – Spanish Fertility Society Register for 2018 and 2019.

Material and methods

The data collected for cycles carried out in 245 Spanish centres in 2018 and 242 centres in 2019 was analysed. The following cycles were studied: IVF/ICSI cycles with fresh own oocytes (2018: 47,083; 2019: 45,836); IVF/ICSI cycles with fresh donor oocytes (2018: 16,357; 2019: 14,457); cycles with cryopreserved embryos (2018: 31,894; 2019: 30,357); PGT (Pre-implementation Genetic Testing) cycles (2018: 10,234; 2019: 14,189) and cycles with cryopreserved oocytes (2018: 8,715; 2019: 9,060).

Results

For IVF/ICSI with fresh own oocytes, a total of 8,968 clinical gestations were obtained in 2018 and 7,894 in 2019, representing a pregnancy rate for fresh embryo transfers of 35.6% and 34.8% respectively. In 2018, 14.4% of these gestations were multiple and 11.9% in 2019. For IVF/ICSI with fresh donor oocytes, 10,157 fresh transfers were performed in 2018 and 8,774 in 2019, which in 2018 resulted in 5,600 clinical gestations (55.1%), of which 13,9% were multiple and in 2019 this resulted in 4,980 clinical gestations (56.8%) with 12.0% multiple gestations. In 2018, 3,797 gestations were obtained (48.9%) from 7,758 cryotransfers for PGT, and in 2019 3,884 gestations were obtained (52.7%) from 7,373 cryotransfers. The number of transfers carried out in 2018 with embryos from vitrified own oocytes was 505 and 6,493 with vitrified donated oocytes. In 2019, there were 581 transfers with vitrified own oocytes and 6,341 with vitrified donor oocytes.

Conclusions

The number of cycles with fresh and cryopreserved oocytes has come to a standstill, both for own and donated oocytes, except for PGT cycles, where the transfer of vitrified rather than fresh embryos is preferred.