印度南部喀拉拉邦胃出口梗阻的人口统计学和病因学模式

V. Sukumar, C. Ravindran, R. Prasad
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引用次数: 25

摘要

背景:在现代,胃出口梗阻(GOO)的主要原因被认为是一种恶性肿瘤,特别是在发达国家。许多书籍和文章确实表明,良性原因仍然是发展中国家粘粘病的主要原因,然而,越来越多的证据证明了相反的情况。男性(更常见)受影响的是女性,在大多数研究中,五、六十岁的个体是主要年龄组。来自南印度的黏液数据很少。目的:回顾性分析具有粘稠特征的患者的内镜检查结果,以确定人口统计学和病因学模式。材料与方法:回顾性分析2005年1月至2014年1月间粘稠性肠胃炎患者的内镜表现。粘稠的诊断是基于临床表现,以及在上内镜检查时无法进入十二指肠第二部分,如内镜记录所示。在内镜检查前已被诊断为恶性肿瘤的患者被排除在研究之外;胃轻瘫患者也是如此。结果:研究期间共342例粘粘症患者接受了内镜检查。良性梗阻的病因以消化性溃疡为主。恶性梗阻的主要原因是胃癌累及远端胃。男女比例为3.2:1。恶性肿瘤患者年龄大于良性疾病患者。大多数患者年龄在60岁和70岁。恶性肿瘤的风险随着年龄的增长而增加,尤其是在女性中。四分之一的胃癌伴有黏液。结论:该研究表明,在印度南部喀拉拉邦,粘粘病的原因主要是恶性肿瘤。病因学和人口学模式与在发达国家进行的研究相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Demographic and Etiological Patterns of Gastric Outlet Obstruction in Kerala, South India
Background: In the modern era, the major cause of gastric outlet obstruction (GOO) is known to be a malignancy, especially in the developed world. Many books and articles do suggest that the benign causes continue to be the major cause of GOO in the developing world however, there is growing evidence proving the contrary. Males were (more commonly) affected females and individuals in their fifth and sixth decade have been the predominant age group in the majority of studies. There is a minimal data of GOO from South India. Aims: A retrospective analysis of the endoscopic findings of patients presenting with features of GOO to determine the demographic and etiological patterns. Materials and Methods: A retrospective study of the endoscopic findings of patients with GOO from January 2005 to January 2014 was done. The diagnosis of GOO was based on clinical presentation, and an inability during the upper endoscopy to enter the second portion of the duodenum as documented in the endoscopy registers. Patients who have already been diagnosed with malignancy prior to the endoscopy were excluded from the study; so were the patients with gastroparesis. Results: A total of 342 patients with GOO underwent the endoscopy during the study period. The causes for benign obstruction were predominantly peptic ulcer disease. The major cause for malignant obstruction was carcinoma of stomach involving the distal stomach. The male to female ratio was 3.2:1. The patients with malignancy were older than patients with benign disorders. Most of the patients were in the sixth and seventh decade. The risk of malignancy was higher with increasing age, especially in women. A fourth of all carcinoma stomach presented with GOO. Conclusion: The study demonstrates that the cause for GOO in Kerala, South India is predominantly malignancy. The etiological and demographic patterns were similar to the studies conducted in the developed nations.
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