草甘膦对人类精子的影响:体外近似

Urologia Colombiana Pub Date : 2021-09-01 DOI:10.1055/s-0041-1731413

Mateo Morales Velásquez, Valentina Velásquez Rivera, W. C. Cardona Maya

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引用次数: 1

摘要

草甘膦是一种用于根除非法作物的除草剂;然而，由于与之相关的各种健康问题，它的使用存在争议。本研究旨在评估草甘膦对体外人类精子的影响。方法选取正常精子健康男性精液样本22份;11份精液样本与Panzer (INVESA s.a.， Antiquia，哥伦比亚)和Roundup (Monsanto Company, MO, USA)孵育。观察其运动性和活力的变化。并对精液的功能参数进行了评价。结果暴露于草甘膦环境下的小鼠活力和活力下降;观察到线粒体膜电位降低，膜脂质过氧化增加。结论根据目前的结果，我们得出草甘膦对接触者具有细胞毒性的结论，并可能影响其生育能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Effect of Glyphosate on Human Sperm: In Vitro Approximation

Abstract Introduction Glyphosate is an herbicide used to eradicate illicit crops; however, its use is controversial due to different health problems associated with it. The present study aims to evaluate the effects of glyphosate on human sperm in vitro. Methods Twenty-two semen samples from healthy normozoospermic men were included; 11 semen samples were incubated with Panzer (INVESA S.A., Antiquia, Colombia) and 11 with Roundup (Monsanto Company, MO, USA). The changes in motility and viability were observed. Functional seminal parameters were evaluated as well. Results The samples exposed to glyphosate showed less motility and viability; a decrease in the potential of the mitochondrial membrane was observed, and an increase in the lipoperoxidation of the membrane was evidenced. Conclusion Based on the present results, we concluded that glyphosate has cytotoxic potential for exposed people and may affect their fertility.

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来源期刊

Urologia Colombiana Medicine-Urology

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： Urología Colombiana is the serial scientific publication of the Colombian Society of Urology at intervals of three issues per year, in which the results of original research, review articles and other research designs that contribute to increase knowledge in medicine and particularly in the specialty of urology.