基于国际放射防护委员会方法和Rospotrebnadzor方法学建议的患者医疗诊断照射辐射风险评估的比较分析

V. V. Kashcheev, E. Pryakhin, A. Menyajlo, M.S. Panin
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摘要

这项工作致力于采用基于国际放射防护委员会(ICRP)建议的方法和Rospotrebnadzor方法学建议(MR 2.6.1.0215-20)中提出的方法,对患者医疗诊断照射的辐射风险评估进行比较分析。在研究过程中,作者分析了用这些方法计算的肿瘤死亡率终生归因风险的计算结果。作为一个例子,在没有对比的情况下,考虑了胸部器官的单通道计算机断层扫描过程。在第一个病例中,使用ICRP出版物103的方法根据以下年龄的男性和女性的器官剂量计算风险值:在22、27、32、37、42、47、52、57、62、67、72、77、82和87岁时进行检查。在第二种情况下,考虑了方法学建议中提出的表格中提供的数据,但没有考虑遗传影响。对两种情况进行了分析:当计算机断层扫描程序之间的有效剂量差异不超过30%时,以及当差异超过30%时。该研究的作者发现,如果有效剂量接近,对于65岁及以上的男性和女性,这两种方法之间的风险评估差异超过1.5倍。如果两种方法之间的剂量差异超过30%,那么在60岁及以上年龄组中观察到的风险差异为1.5倍。在进行风险评估时考虑了年龄和性别特征,并利用了俄罗斯人口的医疗和人口数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative analysis of the assessment radiation risks of medical diagnostic exposure of patients based on the method of the International Commission on Radiological Protection and methodological recommendations of Rospotrebnadzor
This work is devoted to a comparative analysis of the assessment of radiation risks of medical diagnostic exposure of patients using a method based on the recommendations of the International Commission on Radiological Protection (ICRP) and the method presented in the methodological recommendations of Rospotrebnadzor (MR 2.6.1.0215-20). In the course of the study, the authors analyzed the results of calculations of the lifetime attributable risk of oncological mortality calculated by these methods. As an example, the procedure of a single passage of computed tomography of the chest organs without contrast was considered. In the first case, the risk value was calculated using the methodology of ICRP Publication 103 based on organ doses for the following ages of men and women: examination at 22, 27, 32, 37, 42, 47, 52, 57, 62, 67, 72, 77, 82 and at 87 years old. In the second case, the data given in the tables presented in the methodological recommendations were considered, but without considering hereditary effects. The analysis was carried out for two cases: when the difference between effective doses between computed tomography procedures did not exceed 30%, and when the difference was more than 30%. The authors of the work found that the difference in the risk assessment between the two methods exceeds 1.5 times for the age groups of 65 years and older, for men and women, if the effective doses are close. If the difference in dose between the two procedures was more than 30%, then a 1.5-fold difference in risks was observed in age groups 60 years and older. Risk assessment was performed with account of age and gender characteristics, as well as with the use of medical and demographic data of the Russian population.
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