无乳糖配方奶与酸奶治疗急性腹泻患儿的疗效比较

Mahjabeen Akram, Sadam Hussain, Muhammad Wasim Salim, Faizan Pervaiz, S. Karim, H. Khan
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引用次数: 0

摘要

背景:腹泻是巴基斯坦最常见的问题之一,其中开伯尔-普赫图赫瓦省的患病率最高,为28%,其次是信德省(23%)、旁遮普(22%)和俾路支省(12%)。据世卫组织统计,每年有150万5岁以下儿童死于腹泻。因此,本研究旨在观察无乳糖配方奶与自制原味酸奶对急性腹泻儿童的影响。方法:对拉合尔服务医院儿科4 ~ 24月龄儿童60例进行随机对照试验,每组30例。1组给予酸奶,2组给予无乳糖牛奶。腹泻消退时间以小时为单位记录,数据采用SPSS 20进行统计分析。实际意义:比较无乳糖配方奶和酸奶作为急性腹泻儿童饮食干预的实际意义涉及几个考虑因素。首先,应评估腹泻的严重程度和持续时间,以确定适当的干预措施。其次,应考虑到儿童的年龄和营养需要。第三,应考虑无乳糖配方奶和酸奶在当地的可获得性和接受度。此外,每种选择的潜在优点和缺点,如酸奶的营养成分、易消化性和益生菌特性,都需要评估。重要的是咨询医疗保健专业人员,并根据具体情况做出明智的决定,以促进管理儿童急性腹泻的最佳结果。结果:60例患儿中,男26例(43.33%),女34例(56.67%)。1组和2组的平均腹泻缓解时间(结局)分别为43.9±7.30小时和71.57±12.92小时。组1患者治疗后转归与组2患者比较差异有统计学意义(P值= 0.00)。然而,治疗对性别的影响不显著(P值= 0.48)。女性饮用酸奶的结果为43.6±7.5小时,无乳糖牛奶的结果为70.6±8.4小时;男性饮用酸奶的结果为44.3±8.6小时,无乳糖牛奶的结果为73.1±9.1小时。结论:酸奶对腹泻的缓解效果优于无乳糖配方奶。关键词:无乳糖配方奶,自制原味酸奶,腹泻
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Outcome of Lactose-Free Formula Milk with Yogurt in Children with Acute Diarrhea
Background: Diarrhea is one of the most common problems in Pakistan where Khyber Pakhtunkhwa has the maximum prevalence i.e, 28% followed by Sindh (23%), Punjab (22%), and Baluchistan (12%). According to WHO every year 1.5 million children under 5 years, die just because of diarrhea. Therefore, this study aimed to look at the effect of lactose-free formula milk versus homemade plain yogurt in children with acute diarrhea. Methods: A randomized controlled trial was carried out on 60 children of age 4-24 months, 30 in each group in the Department of Pediatrics, Services Hospital Lahore. Group 1 was given yogurt while lactose-free milk was given to group 2. The duration of resolution of diarrhea was noted in hours and data was statistically analyzed using SPSS version 20. Practical Implication: The practical implication of comparing lactose-free formula milk with yogurt as a dietary intervention for children with acute diarrhea involves several considerations. Firstly, the severity and duration of diarrhea should be evaluated to determine the appropriate intervention. Secondly, the age and nutritional needs of the child should be taken into account. Thirdly, the availability and acceptance of lactose-free formula milk and yogurt in the local context should be considered. Additionally, the potential benefits and drawbacks of each option, such as the nutritional content, ease of digestion, and probiotic properties of yogurt, need to be assessed. It is important to consult with healthcare professionals and make an informed decision based on the specific circumstances to promote optimal outcomes in managing acute diarrhea in children. Results: Out of 60 children, 26 (43.33%) were male and 34 (56.67%) were female. In groups 1 and 2, the mean duration of resolution of diarrhea (outcome) was 43.9 ± 7.30 hours and 71.57 ± 12.92 hours respectively. Group 1 patients’ treatment showed a significant difference in the outcome than group 2 patients (P value= 0.00). However, the treatment effect on gender was found non-significant (P value= 0.48). The outcome in females was 43.6 ± 7.5 hours with yogurt and 70.6 ± 8.4 hours with lactose-free milk while in males the outcome was 44.3 ± 8.6 hours with yogurt and 73.1 ± 9.1 hours with lactose-free milk. Conclusion: The use of yogurt is better than lactose-free formula milk for the resolution of diarrhea. Keywords: Lactose-free formula milk, homemade plain yogurt, diarrhea.
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