全方位反击,征服肺癌

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
S. Jang
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引用次数: 0

摘要

背景:随着人口老龄化,肺癌呈指数增长。为了战胜肺癌,早期诊断,开发新的治疗方法,并结合多学科治疗方式是必不可少的。当前概念:自从国家肺癌高危人群低剂量胸部ct筛查项目启动以来,肺癌的早期诊出率有望提高。免疫检查点抑制剂和靶点药物的发展在生产新的抗癌药物方面取得了成功。免疫检查点抑制剂在各种临床情况下与现有治疗方式联合使用,例如不仅用于转移性肺癌患者,还用于可切除肺癌患者和手术不可切除的局部晚期疾病患者。这些试验显著地改善了生存结果。靶向抗癌药物的开发也在快速推进。当靶向抗癌药物单独使用或与常规疗法联合使用时,具有特定基因突变的肺癌患者的存活率大大提高。讨论与结论:肺癌的早期诊断和新的治疗方式的发展极大地改善了肺癌患者的预后。应继续尝试将传统和新的治疗方式结合起来。有必要讨论改变长期幸存者的医疗政策,这将不可避免地增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
All-round counterattack to conquer lung cancer
Background: Lung cancer is increasing exponentially as the population ages. To conquer lung cancer, early diagnosis, developing new treatments, and combining multidisciplinary treatment modalities are essential.Current Concepts: Since the national lung cancer screening program for high-risk individuals using low-dose chest computed tomography has launched, the rate of early diagnosis of lung cancer is expected to increase. The development of immune checkpoint inhibitors and target agents is paying off in terms of producing new anticancer drugs. Immune checkpoint inhibitors are administered in combination with existing treatment modalities in various clinical situations, such as for not only patients with metastatic lung cancer but also for those with resectable lung cancer and with surgically unresectable locally advanced disease. These trials dramatically improved survival outcomes. The development of targeted anticancer drugs is also advancing at a rapid pace. The survival rate of patients with lung cancer who have specific gene mutations has greatly improved when targeted anticancer drugs are administered alone or in combination with conventional therapies.Discussion and Conclusion: Early diagnosis of lung cancer and the development of new treatment modalities are greatly improving the prognosis of patients with lung cancer. Attempts to combine conventional and new treatment modalities should continue. It is necessary to discuss changing medical policies for long-term survivors, which will inevitably increase.
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来源期刊
Journal of The Korean Medical Association
Journal of The Korean Medical Association Medicine-General Medicine
CiteScore
0.50
自引率
0.00%
发文量
84
审稿时长
4-8 weeks
期刊介绍: The Journal of the Korean Medical Association (JKMA) is the official peer-reviewed, open-access, monthly journal of the Korean Medical Association (KMA). It contains articles in Korean or English. Its abbreviated title is ''J Korean Med Assoc''. The aims of the Journal include contributing to the treatment of and preventing diseases of public health importance and to improvement of health and quality of life through sharing the state-of the-art scientific information on medicine by the members of KMA and other national and international societies.
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