肺癌术后发生心律失常的危险因素及临床处理

G. Bablekos, S. Michaelides
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引用次数: 0

摘要

在这篇简短的综述中,我们试图分析和讨论促进肺癌手术后出现室上性心律失常(SVDs)的危险因素,以及适当的临床处理,这些危险因素可能会对这些患者的术后临床结果产生负面影响。通过检索近三十年(1990年1月1日至2017年11月30日)的相关国际文献,最终根据标题和摘要从101篇符合条件的文章中筛选出30篇。使用的关键词如下:心律失常,心脏(Mesh),肺肿瘤/手术(Mesh),术后并发症(Mesh),术后时间(Mesh)。自主神经系统张力受胸外科创伤程度的影响,对心房的影响,对于svd的触发是至关重要的。此外,胺碘酮似乎是一种安全有效的药物,可以保护或恢复肺癌手术引起的窦性心律紊乱。除胺碘酮外,其他药物如洋地黄、维拉帕米、地尔硫卓和β受体阻滞剂不应在出现沃尔夫-帕金森-怀特综合征的患者胸外科手术后使用。维拉帕米和地尔硫卓是静脉注射β受体阻滞剂或出现充血性心力衰竭患者的禁忌症。本文还讨论了胸腔手术后复律在心律失常恢复中的作用以及抗凝治疗的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk Factors and Clinical Management of Cardiac Arrhythmias Arising After Lung Cancer Surgery
In the present short review it is attempted to analyze and discuss, along with the appropriate clinical management, the risk factors promoting the emergence of supraventricular cardiac dysrhythmias (SVDs) after lung cancer surgery that may negatively influence the postoperative clinical outcome of these patients. By searching the relevant international literature of the last three decades (from January 1st 1990 to November 30th 2017) 30 out of 101 eligible articles were finally selected on the basis of their title and abstract. The key words which had been used are as follows: Arrhythmias, Cardiac (Mesh), Lung Neoplasms/Surgery (Mesh), Postoperative Complications (Mesh), Postoperative Period (Mesh). The impact of the autonomous nervous system tone, being influenced by the extent of thoracic surgical trauma, on the atria, is of paramount importance regarding the triggering of SVDs. Moreover, it seems that amiodarone constitutes a safe and efficient agent to either protect or restore disturbances of the sinus rhythm resulting from lung cancer surgery. Other medicines such as digitalis, verapamil, diltiazem and beta-blockers, with the exception of amiodarone, should not be administered after thoracic surgery in patients presenting Wolf-Parkinson-White syndrome. Verapamil and diltiazem is contraindicated in patients intravenously receiving beta-blockers or presenting congestive heart failure. The role of cardioversion to restore cardiac arrhythmias after thoracic surgery is also discussed along with the role of anti-coagulation treatment.
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