肝移植术后的生活质量

B. Das, Mohammed Mostafizur Rahman, Khan Zr
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引用次数: 0

摘要

我们通过互联网检索了世界各地发表的关于肝移植后生活质量(Qol)的文章;通过我们的搜索过程,可以找到38篇文章。在回顾所有文献后,我们发现没有专门的评估工具来衡量肝移植后的生活质量。一般工具用于评估这些患者的生活质量。与正常健康志愿者相比,移植前的生活质量受到严重影响。肝细胞癌和胆汁淤积病因的生活质量评分高于与酒精或病毒性肝炎相关的病因。移植后生活质量评分不受原始肝硬化病因的影响,但移植受体评分继续保持显著!)。低于健康患者对照组。肝移植术后初期生活质量评分有所提高,但长期生活质量评分下降。这可能是由于随着患者年龄的增长,身体功能和身体疼痛领域的下降,长期摄入类固醇导致骨质疏松症,以及慢性排斥反应。同时指出丙型肝炎患者肝移植术后生活质量不佳。开发移植特异性的生活质量评估工具可以帮助更准确地评估改变移植后生活质量的因素。外科杂志(2014)Vol. 18 (2): 67-77
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quality of Life after Liver Transplantation
We have searched articles published in various journals world wide on quality of life (Qol) after liver transplantation through internet; 38 articles were available through our searching process. After reviewing all papers we have found that there is no transplant specific assessment tool for measuring Qol after liver transplantation. General tools are used for assessment of Qol of these patients. PretransplantationQol are severely affected when compared to normal healthy volunteers. Hepatocellular carcinoma and cholestatic etiologies have higher Qol scores than those related to alcohol or viral hepatitis. Post-transplantation Qol scores are not affected by the etiology of the original liver cirrhosis, but transplant recipient scores continue to remain significant!)'. lower than those of healthy patient controls. The Qol scores improve during initial time after liver transplantation, but decreases in the long term. It may be due to decreases in the physical function and bodily pain domains as the patient's age increases, develops osteoporosis from long-term intake of steroids, and chronic rejection process. It is also addressed that Qol is not good in patients with Hepatitis C after liver transplantation. The development of a Qol assessment tool specific to transplantation could help to more accurately assess factors that alter post-transplantation Qol. Journal of Surgical Sciences (2014) Vol. 18 (2) : 67-77
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