基于深度学习的双源螺旋ct图像特征评价他汀类药物治疗冠状动脉斑块的疗效

Sci. Program. Pub Date : 2022-01-07 DOI:10.1155/2022/1810712
Weizhong Yu, Haixia Ji, Qingjun Tan
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引用次数: 0

摘要

本研究旨在探讨基于深度学习的双源螺旋计算机断层扫描(DSCT)图像在评估他汀类药物治疗冠状动脉斑块疗效中的作用。本研究提出了一种卷积神经网络(CNN)算法。在此基础上对模型进行改进,应用Res-Net网络重建CT图像,构建深度学习网络模型Mask R-CNN增强图像重建能力。然后选取80例住院治疗的冠心病患者作为研究对象,分为对照组(n = 40)和观察组(n = 40)。对照组男性21例,女性19例,平均年龄52±3.2岁;观察组男性24例,女性16例,平均年龄51±2.4岁。观察组采用所建模型重建,对照组采用传统CT。两次检查间隔6 ~ 12个月,平均间隔8±1.78个月。在此期间,所有患者均接受以阿托伐他汀为主的保守治疗。两组一般资料比较,差异无统计学意义(P > 0.05)。建立网络模型测量患者的冠状动脉斑块和血管体积,并在Res-Net网络上重建图像。Res-Net网络的损失值稳定在最低水平0.02左右,在训练过程中表现出非常快的效果。他汀类药物治疗后,患者血管体积、冠状动脉斑块体积均明显减小(P < 0.05)。在网络模型中花费的平均时间为1.20秒。A、B、C医生测量每个椎间盘的平均时间分别为186秒、158秒、142秒。网络模型的构建显著提高了CT图像的诊断和处理速度。综上所述,本研究提出的Res-Net网络模型对双源CT (DSCT)图像分割具有一定的可行性和有效性,能够有效提高冠状动脉疾病患者CT图像的临床信息评价,对智能医疗设备的发展具有重要的参考价值。为临床预测和诊断冠心病(CAD)提供了新的诊断方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the Efficacy of Statins in the Treatment of Coronary Artery Plaque Using Dual-Source Spiral Computed Tomography Image Features under Deep Learning
This study aimed at discussing deep learning-based dual-source spiral computed tomography (DSCT) image in the evaluation of the efficacy of statins in the treatment of coronary artery plaque. A convolutional neural network (CNN) algorithm was proposed in this study. On this basis, the model was improved, the Res-Net network was applied to reconstruct the computed tomography (CT) image, and the deep learning network model Mask R-CNN was constructed to enhance the ability of image reconstruction. Then, 80 patients with coronary artery disease who were treated in hospital were selected as the research objects and divided into a control group (n = 40) and an observation group (n = 40). There were 21 male patients and 19 female patients in the control group, with an average age of 52 ± 3.2 years; there were 24 male patients and 16 female patients in the observation group, with an average age of 51 ± 2.4 years. The observation group was reconstructed with the constructed model, and patients in the control group received traditional CT. The interval between two examinations was 6–12 months, with an average interval of 8 ± 1.78 months. During the interval, all patients received conservative treatment mainly with atorvastatin. The general data of the two groups were comparable without statistical significance ( P > 0.05 ). A network model was constructed to measure the coronary plaque and vascular volume of the patients, and the images were reconstructed on the Res-Net network. The loss value of Res-Net network was stable at the lowest level around 0.02, showing a very fast effect in the training process. After statin treatment, the vascular volume and coronary plaque volume of the patients were decreased obviously ( P < 0.05 ). The average time spent in the network model was 1.20 seconds. The average time spent in the measurement of each disc by doctors A, B, and C was 186 seconds, 158 seconds, and 142 seconds, respectively. The construction of network model markedly improved the speed of CT image diagnosis and treatment. In conclusion, the Res-Net network model proposed in this study had certain feasibility and effectiveness for dual-source CT (DSCT) image segmentation and could effectively improve the clinical information evaluation of CT images from patients with coronary artery disease, which had important reference value for the development of intelligent medical equipment. It could provide a new diagnostic method for clinical prediction and diagnosis of coronary artery disease (CAD).
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