光子放射治疗在儿科实践中的现代趋势

Q4 Medicine

Pediatriya - Zhurnal im G.N. Speranskogo Pub Date : 2023-06-01 DOI:10.24110/0031-403x-2023-102-3-124-130

A. Nechesnyuk, A. Loginova, A. Rumyantsev, S.V. Kazyukov

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引用次数: 0

摘要

放射治疗(RT)的新技术正在迅速发展，并进入领先诊所的临床实践。儿科医生、儿科肿瘤学家、血液学家和其他医生需要了解现代放射治疗在儿科实践中发展的主要趋势。本文介绍了光子放射治疗(PRT)的主要现代方法，特别是具有强度调制和图像控制的放射治疗方法，并讨论了自适应和立体定向的放射治疗方法，并论证了迫切需要对儿科患者的放射计划进行参考评价。因此，根据40个诊所的270个方案的参考评价结果，39%的病例发现目标轮廓存在严重错误，40%的病例发现方案不能被接受治疗。现代PRT具有广泛的技术能力，然而，为了更有效地利用它，使患者受益，有必要建立一个统一的国家RT计划数据库。只有对新数据进行分析，才有可能采取更平衡的方法来规划儿童暴露，在考虑到不良晚期效应的可能性的情况下，为不同预后组的患者提供剂量减少/增加。

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Modern trends in photon radiation therapy in pediatric practice

New technologies in radiation therapy (RT) are rapidly developing and entering the clinical practice of leading clinics. Pediatricians, pediatric oncologists, hematologists and other physicians are in need of understanding of the main trends in the development of modern RT in pediatric practice. The Article describes the main modern methods of photon radiation therapy (PRT) and of RT with intensity modulation and image control in particular, considers the methods of adaptive and stereotaxic RT. The urgent need for a reference evaluation of irradiation of pediatric patients’ plans is demonstrated as well. Thus, according to the reference evaluation results of 270 plans from 40 clinics, it was found that gross errors in target contouring were found in 39% of cases, the plan that could not be accepted for treatment in 40%. Modern PRT has wide technological capabilities, however, for its more effective use for the benefit of patients it is necessary to create a unified national database of RT plans. Only an analysis of the new data can make it possible to take more balanced approach to planning exposure in children, to provide dose reduction/escalation in patients of various prognostic groups taking into account the likelihood of undesirable late effects.

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来源期刊

Pediatriya - Zhurnal im G.N. Speranskogo Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

150

期刊介绍： Journal “Pediatria” named after G.N. Speransky (the official short names of the Journal are “Journal «Pediatria»,” “Pediatria,” and “«Pediatria,» the Journal”) is the oldest Soviet-and-Russian (in the Russian Federation, the CIS and former Soviet Union) scientific and practical medical periodical assigned for pediatricians that is published continuously since May, 1922, and distributed worldwide. Our mission statement specifies that we aim to the ‘raising the level of skills and education of pediatricians, organizers of children’s health protection services, medicine scientists, lecturers and students of medical institutes for higher education, universities and colleges worldwide with an emphasis on Russian-speaking audience and specific, topical problems of children’s healthcare in Russia, the CIS, Baltic States and former Soviet Union Countries and their determination with the use of the World’s best practices in pediatrics.’ As part of this objective, the Editorial of the Journal «Pediatria» named after G.N. Speransky itself adopts a neutral position on issues treated within the Journal. The Journal serves to further academic discussions of topics, irrespective of their nature - whether religious, racial-, gender-based, environmental, ethical, political or other potentially or topically contentious subjects. The Journal is registered with the ISSN, - the international identifier for serials and other continuing resources, in the electronic and print world: ISSN 0031-403X (Print), and ISSN 1990-2182 (Online). The Journal was founded by the Academician, Dr. Georgiy Nestorovich SPERANSKY, in May, 1922. Now (since 1973) the Journal bears his honorary name.