喀麦隆西南地区三级医院2型糖尿病患者血脂分布模式

Journal of diabetes & metabolism Pub Date : 2018-05-29 DOI:10.4172/2155-6156.1000795

Mboh Epanda Achille, N. Michel, Sama Leonard Fonkeng, Wam Elvis Chongsi, Panni Asongwed Patrice, Mouladje Maurice, Mouliom Njikam Réné, T. C. Bonglavnyuy

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引用次数: 2

摘要

糖尿病(DM)被认为是一个严重的全球健康问题，经常与一些可改变的危险因素相关的致残和危及生命的并发症有关。其中一个可改变的因素是血脂异常。由于检测和治疗血脂异常是降低心血管疾病(CVD)风险的一种手段，因此测定糖尿病患者的血脂水平现在被认为是一种标准护理。对108例糖尿病患者的血脂和空腹血糖进行了测定。使用国家胆固醇教育计划-成人治疗小组III (NCEP-ATP III)标准定义血脂异常。测量BMI和腰围。体重指数平均值为29.85±6.32 kg/m2，男性27。23±5.29 kg/m2，雌性为30。90±6.43 kg/m2。男性平均DM病程为57.80±13.72个月，女性平均DM病程为6.58±7.11个月。男性患者腰围≥120 cm者23例(74.19%)，腰围≥Â， 120 cm者8例(25.81%);女性患者腰围≥88 cm者64例(83.12%)，腰围≥Â， 88 cm者13例(16.88%)。女性患者TC(4.77±1.13 vs 5.13±1.24 P=0.1711)、LDL-C(2.79±0.95 vs 2.98±1.25 P=0.4016)均值略高于男性，但差异无统计学意义;男性患者HDL-C(1.53±0.50 vs 1.40±0.42 P=0.2006)、TG(1.35±0.66 vs 0.61±0.18 P=0.3424)均值高于女性，但差异无统计学意义。98例糖尿病患者至少有一种或另一种脂质值超出临床目标，患病率为88.89%。最常见的脂质组合为↑TC+↑ldl。人体测量指数与血脂无显著相关性。认识到高脂血症和由此产生的大血管疾病甚至可以在2型糖尿病的“糖尿病前期”发展是很重要的。因此，在糖尿病患者的管理中，早期发现和纠正血脂异常状态是必不可少的。

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Pattern of Lipid Profile of Type 2 Diabetes Patients in Tertiary Hospital South-West Region of Cameroon

Diabetes mellitus (DM) is recognized as a serious global health problem and frequently associated with disabling and life-threatening complications related to some modifiable risk factors. One of the modifiable factors is dyslipidemia. Because detection and treatment of dyslipidemia is one means of reducing cardiovascular disease (CVD) risk, determination of serum lipid levels in people with diabetes is now considered a standard of care. Lipid profile and fasting blood sugar (FBS) of 108 diabetic subjects were assessed. Dyslipidaemia was defined using the national cholesterol education programme–adult treatment panel III (NCEP-ATP III) criteria. BMI and waist circumferences were measured. The mean of the body mass index was 29.85 ± 6.32 kg/m2 with the males having 27. 23 ± 5.29 kg/m2 while the females had 30. 90 ± 6.43 kg/m2. The mean duration of DM was 57.80 ±13.72 month for males while for females it was 6.58 ± 7.11 month. Also 23(74.19%) of the male patients had a waist circumference ≥ 120 cm and 8(25.81%) had a waist circumference A‹Â‚120 cm while for female patients, 64(83.12%) had waist circumference ≥ 88 cm and 13(16.88%) had a waist circumference A‹Â‚88 cm. The mean TC (4.77 ± 1.13 vs 5.13 ± 1.24 P=0.1711) and LDL-C (2.79 ± 0.95 vs 2.98 ± 1.25 P=0.4016) were slightly higher among the female subjects but the differences were not significant from males, while HDL-C (1.53 ± 0.50 vs 1.40 ± 0.42 P=0.2006) and TG (1.35 ± 0.66 vs 0.61 ± 0.18 P=0.3424) were higher among the male subjects but were not statistically different from the females. Ninety-eight diabetic patients had at-least one lipid value or the other outside of the clinical target giving it a prevalence of 88.89%. The most frequent lipid combination was ↑TC+↑LDLc. There was no significant correlations between the anthropometric indices and the lipid profile. It is important to realise that hyperlipidaemia and the resultant macro vascular disease can develop even in the 'prediabetic phase' of type 2 DM. Hence, early detection and correction of dyslipidaemic state is essential in the management of diabetic patients.

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Journal of diabetes & metabolism

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