大肠杆菌焦焦测序DNA样本的时间敏感分层聚类:一个案例研究

2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW) Pub Date : 2011-11-12 DOI:10.1109/BIBM.2011.99

Aldrin Montana, Alex Dekhtyar, Emily R. Neal, Michael Black, C. Kitts

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引用次数: 9

摘要

在计算生物学中，分层聚类是一种比较测序菌株DNA和确定属于同一菌株的细菌分离株的方法。然而，分层聚类的结果有时难以阅读和解释。本文是一个使用改进的分层聚类算法的案例研究，该算法考虑到它所应用的细菌DNA分离收集的潜在结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Chronology-Sensitive Hierarchical Clustering of Pyrosequenced DNA Samples of E. coli: A Case Study

Hierarchical clustering is used in computational biology as a method of comparing sequenced bacterial strain DNA and determining bacterial isolates that belong to the same strain. However, the results of the hierarchical clustering are, at times, difficult to read and interpret. This paper is a case study for the use of a modified hierarchical clustering algorithm, which takes into account the underlying structure of the bacterial DNA isolate collection to which it is applied.

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2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)

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