某三级医院CD4计数≤100 Cells/mm3的HIV感染者隐球菌血症的流行情况

Q4 Medicine

Infection Epidemiology and Microbiology Pub Date : 2022-02-01 DOI:10.52547/iem.8.1.53

P. Kaur, Japsimran Kaur

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引用次数: 0

摘要

本研究旨在了解51 ~ 100岁患者的心功能。此外，55例(55%)患者接受了抗逆转录病毒治疗(ART)， 45例(45%)患者接受了ART naï治疗。约56%的患者没有机会性感染，37%的患者患有肺结核。3份样本LFA阳性，阳性率为3%，而只有1份培养样本隐球菌阳性。然而，CD4计数低与血清隐球菌抗原血症阳性密切相关。结论:本研究表明隐球菌抗原血症是一个健康问题，世卫组织推荐的隐球菌抗原筛查和治疗政策应在当前环境下对在抗逆转录病毒治疗中心登记的艾滋病毒患者常规执行，特别是对抗逆转录病毒治疗naï阳性和CD4细胞计数≤100细胞/毫米的患者

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Prevalence of Cryptococcaemia in HIV Infected Patients with CD4 Counts of ≤100 Cells/mm3-A Cross Sectional Study in a Tertiary Care Hospital

study aimed to investigate the of in patients of 51-100. Also, 55 patients (55%) received antiretroviral therapy (ART), and 45 (45%) cases were ART naï�ve. About 56% of patients had no opportunistic infections, and 37% had pulmonary tuberculosis. Three samples were positive in LFA, showing a prevalence of 3%, while only one of the culture samples was positive for Cryptococcus species. However, low CD4 count was found to be strongly correlated with positive serum cryptococcal antigenemia. Conclusion: The present study reveals that cryptococcal antigenemia is a health problem, and that cryptococcal antigen screening and treatment policy recommended by WHO should be performed routinely for HIV patients registered in ART centres in the current setting, especially for those who are ART naï�ve and have CD4 counts of ≤100 cells/mm

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来源期刊

Infection Epidemiology and Microbiology Medicine-Epidemiology

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

6 weeks