A Quantum-Inspired Biotelemetry System for Robust and Ultrasensitive Wireless Intracranial Pressure Monitoring

We herein introduce a new wireless biotelemetry technique inspired by symmetries in quantum theory to significantly improve the sensitivity and robustness of wireless interrogation of implanted sensors. The proposed telemetric sensor system, consisting of a passive implantable sensor inductively coupled to an active reader, is invariant under the combined parity (P), time (T) and reciprocal scaling (X) transformations and exhibits an exotic eigenvalue bifurcation effect that can greatly enhance the resulting sensitivity. Moreover, the X transformation allows robust wireless readout of a highly lossy bioimplant with a good resolvability, not possible with conventional biotelemetry techniques. We demonstrate the proposed concept with in-vitro assessment of the intracranial pressure (ICP) monitoring system comprising a battery-free wireless pressure sensor for traumatic brain injury patients.