Investigation of the relation of maternal serum endocan levels to preeclampsia presence and severity

Abstract Background: Endocan was shown to be a possible predictor of vascular endothelium related diseases. Due to this fact we aimed to investigate the role of maternal serum endocan levels in preeclampsia presence and severity. Methods: A total of 70 patients, including 25 normal pregnant women and 45 patients with preeclampsia (consists of 25 mild and 20 severe preeclamptic women), were included in this study. Maternal serum endocan concentrations were measured and compared among groups and subgroups. Results: Levels of endocan were detected statistically higher in the preeclamptic group than the control group. Endocan levels were lower in the severe preclampsia group than the mild preeclampsia group but this was not detected statistically significant. Conclusions: Maternal serum endocan levels can be used as a biomarker for preeclampsia presence.