Effect of high-intensity interval training and Aloe vera consumption on serum adiponectin and beta cells function in diabetic male rats

Background: Exercise training and the use of medicinal plants are helpful in the prevention and treatment of diabetes. The purpose of this study was to evaluate effect of eight-week high-intensity interval training and Aloe vera consumption on serum adiponectin and beta cells function in diabetic male rats. Materials and methods: In this experimental study, 32 diabetic Wistar rats with STZ (weight of 240-260 grams and an average age of 12 weeks) were randomly divided into four groups, including the “control group”, the “training group”, the “supplement group” and the “training + supplement group”. Training group was exposed to high-intensity interval training with %90 VO2max intensity for 8 weeks and 5 sessions per week for 2 to 6 minutes per session. Supplement group received 300 mg of Aloe vera daily for 8 weeks, five times a week. Data were analyzed using one-way ANOVA. Results: Eight weeks of high intensity interval training with Aloe vera supplementation resulted in a significant increase in adiponectin and insulin in diabetic male rats (P<0.05). But there was no significant difference in glucose and beta cell function (P>0.05). Conclusion: According to the findings of the present research, it seems that high intensity interval training along with Aloe vera supplementation may help to increase adiponectin and insulin and also improve diabetes control.