新生儿sars-cov-2引起冠状病毒感染临床过程的特点

L. Kolyubakina, O. V. Vlasova, N. Kretsu, Е.Z. Trekush
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引用次数: 1

摘要

在SARS-CoV-2大流行年,科学文献发表了大量关于病原体的流行病学特征、疾病的临床和临床旁特征、诊断原则和治疗方法的资料。但关于新生儿冠状病毒感染的流行病学和临床特征仍有许多未解决的问题。目的:在切尔诺夫茨地区儿童临床医院RCNE的基础上,对2020年收治的新生儿SARS-CoV-2冠状病毒感染的特点进行观察研究。材料和方法。为达到研究目的,回顾性分析12例住院新生儿的医疗记录。纳入标准:年龄0-28天,经鼻咽涂片SARSCoV-2冠状病毒感染聚合酶链反应(PCR)阳性检测证实。患儿入院时平均年龄为13.6±2.1 d,每3名新生儿(33.3%)在10 d前入院。农村居民占66.6%,女童占75%。据调查,大多数新生儿与新冠肺炎患者的接触都得到了证实。多数患儿平均在发病后第2天从家中入院,临床症状以急性呼吸道病毒感染为主,发病时仅2例患者出现胃肠道症状。病情进展顺利。随访婴儿全血细胞计数的变化需要进一步的动态临床和临床旁观察。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PECULIARITIES OF CORONAVIRUS INFECTION CLINICAL COURSE CAUSED BY SARS-COV-2 IN NEWBORNS
A lot of data concerning the epidemiological features of the pathogen, clinical andparaclinical characteristics of the disease, principles of diagnosis and approaches tothe treatment have been published in the scientific literature during the year of pandemiacaused by SARS-CoV-2. But still there are many unresolved issues regarding theepidemiological and clinical characteristics of this coronavirus infection in newborns.Purpose – to conduct observational study of the peculiarities of SARS-CoV-2 coronavirusinfection in newborns treated during 2020 on the basis of RCNE "Chernivtsi RegionalChildren's Clinical Hospital", Chernivtsi.Material and methods. Analysis of medical records of 12 inpatient newborns wasconducted retrospectively to achieve the goal of the study. Inclusion criteria: age 0-28days of life, confirmed by positive test of polymerase chain reaction (PCR) for SARSCoV-2 coronavirus infection of a nasopharyngeal smear. The average age of childrenat the time of admission was 13.6 ± 2.1 days, every third newborn child (33.3%) wasadmitted before the age of 10 days old. The portion of rural residents was 66.6%, girls(75%) predominated among children who fell ill.Results. It has been revealed that in most cases the contact of newborns with COVID-19patients was confirmed. Mostly children were admitted from home on average onthe second day after the onset of the disease, predominantly with the typical clinicalsymptoms of acute respiratory viral infection, at the onset of the disease gastrointestinalmanifestations prevailed in only two of patients. The course of the disease was favorable.Conclusions. The detected changes in the follow-up infants’ complete blood count requirefurther dynamic clinical and paraclinical observation.
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