L. Kolyubakina, O. V. Vlasova, N. Kretsu, Е.Z. Trekush
{"title":"新生儿sars-cov-2引起冠状病毒感染临床过程的特点","authors":"L. Kolyubakina, O. V. Vlasova, N. Kretsu, Е.Z. Trekush","doi":"10.24061/1727-4338.XX.1.75.2021.9","DOIUrl":null,"url":null,"abstract":"A lot of data concerning the epidemiological features of the pathogen, clinical andparaclinical characteristics of the disease, principles of diagnosis and approaches tothe treatment have been published in the scientific literature during the year of pandemiacaused by SARS-CoV-2. But still there are many unresolved issues regarding theepidemiological and clinical characteristics of this coronavirus infection in newborns.Purpose – to conduct observational study of the peculiarities of SARS-CoV-2 coronavirusinfection in newborns treated during 2020 on the basis of RCNE \"Chernivtsi RegionalChildren's Clinical Hospital\", Chernivtsi.Material and methods. Analysis of medical records of 12 inpatient newborns wasconducted retrospectively to achieve the goal of the study. Inclusion criteria: age 0-28days of life, confirmed by positive test of polymerase chain reaction (PCR) for SARSCoV-2 coronavirus infection of a nasopharyngeal smear. The average age of childrenat the time of admission was 13.6 ± 2.1 days, every third newborn child (33.3%) wasadmitted before the age of 10 days old. The portion of rural residents was 66.6%, girls(75%) predominated among children who fell ill.Results. It has been revealed that in most cases the contact of newborns with COVID-19patients was confirmed. Mostly children were admitted from home on average onthe second day after the onset of the disease, predominantly with the typical clinicalsymptoms of acute respiratory viral infection, at the onset of the disease gastrointestinalmanifestations prevailed in only two of patients. The course of the disease was favorable.Conclusions. The detected changes in the follow-up infants’ complete blood count requirefurther dynamic clinical and paraclinical observation.","PeriodicalId":12291,"journal":{"name":"Experimental pathology","volume":"92 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"PECULIARITIES OF CORONAVIRUS INFECTION CLINICAL COURSE CAUSED BY SARS-COV-2 IN NEWBORNS\",\"authors\":\"L. Kolyubakina, O. V. Vlasova, N. Kretsu, Е.Z. Trekush\",\"doi\":\"10.24061/1727-4338.XX.1.75.2021.9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A lot of data concerning the epidemiological features of the pathogen, clinical andparaclinical characteristics of the disease, principles of diagnosis and approaches tothe treatment have been published in the scientific literature during the year of pandemiacaused by SARS-CoV-2. But still there are many unresolved issues regarding theepidemiological and clinical characteristics of this coronavirus infection in newborns.Purpose – to conduct observational study of the peculiarities of SARS-CoV-2 coronavirusinfection in newborns treated during 2020 on the basis of RCNE \\\"Chernivtsi RegionalChildren's Clinical Hospital\\\", Chernivtsi.Material and methods. Analysis of medical records of 12 inpatient newborns wasconducted retrospectively to achieve the goal of the study. Inclusion criteria: age 0-28days of life, confirmed by positive test of polymerase chain reaction (PCR) for SARSCoV-2 coronavirus infection of a nasopharyngeal smear. The average age of childrenat the time of admission was 13.6 ± 2.1 days, every third newborn child (33.3%) wasadmitted before the age of 10 days old. The portion of rural residents was 66.6%, girls(75%) predominated among children who fell ill.Results. It has been revealed that in most cases the contact of newborns with COVID-19patients was confirmed. Mostly children were admitted from home on average onthe second day after the onset of the disease, predominantly with the typical clinicalsymptoms of acute respiratory viral infection, at the onset of the disease gastrointestinalmanifestations prevailed in only two of patients. The course of the disease was favorable.Conclusions. The detected changes in the follow-up infants’ complete blood count requirefurther dynamic clinical and paraclinical observation.\",\"PeriodicalId\":12291,\"journal\":{\"name\":\"Experimental pathology\",\"volume\":\"92 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-05-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Experimental pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24061/1727-4338.XX.1.75.2021.9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24061/1727-4338.XX.1.75.2021.9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
PECULIARITIES OF CORONAVIRUS INFECTION CLINICAL COURSE CAUSED BY SARS-COV-2 IN NEWBORNS
A lot of data concerning the epidemiological features of the pathogen, clinical andparaclinical characteristics of the disease, principles of diagnosis and approaches tothe treatment have been published in the scientific literature during the year of pandemiacaused by SARS-CoV-2. But still there are many unresolved issues regarding theepidemiological and clinical characteristics of this coronavirus infection in newborns.Purpose – to conduct observational study of the peculiarities of SARS-CoV-2 coronavirusinfection in newborns treated during 2020 on the basis of RCNE "Chernivtsi RegionalChildren's Clinical Hospital", Chernivtsi.Material and methods. Analysis of medical records of 12 inpatient newborns wasconducted retrospectively to achieve the goal of the study. Inclusion criteria: age 0-28days of life, confirmed by positive test of polymerase chain reaction (PCR) for SARSCoV-2 coronavirus infection of a nasopharyngeal smear. The average age of childrenat the time of admission was 13.6 ± 2.1 days, every third newborn child (33.3%) wasadmitted before the age of 10 days old. The portion of rural residents was 66.6%, girls(75%) predominated among children who fell ill.Results. It has been revealed that in most cases the contact of newborns with COVID-19patients was confirmed. Mostly children were admitted from home on average onthe second day after the onset of the disease, predominantly with the typical clinicalsymptoms of acute respiratory viral infection, at the onset of the disease gastrointestinalmanifestations prevailed in only two of patients. The course of the disease was favorable.Conclusions. The detected changes in the follow-up infants’ complete blood count requirefurther dynamic clinical and paraclinical observation.