饮食中硝酸盐在维持全身和口腔健康中的作用

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
U. Schlagenhauf
{"title":"饮食中硝酸盐在维持全身和口腔健康中的作用","authors":"U. Schlagenhauf","doi":"10.3390/dj10050084","DOIUrl":null,"url":null,"abstract":"The assessment of the significance of nitrates ingested with food has undergone a fundamental change in recent years after many controversial discussions. While for a long time, a diet as low in nitrates as possible was advocated on the basis of epidemiological data suggesting a cancer-promoting effect of nitrate-rich diets, more recent findings show that dietary nitrate, after its conversion to nitrite by nitrate-reducing bacteria of the oral microbiota, is an indispensable alternative source for the formation of nitric oxide (NO), which comprises a key element in the physiology of a variety of central body functions such as blood pressure control, defense against invading bacteria and maintenance of a eubiotic microbiota in the gut and oral cavity. This compact narrative review aims to present the evidence supported by clinical and in vitro studies on the ambivalent nature of dietary nitrates for general and oral health and to explain how the targeted adjuvant use of nitrate-rich diets could open new opportunities for a more cause-related control of caries and periodontal disease.","PeriodicalId":47284,"journal":{"name":"Open Dentistry Journal","volume":"11 1","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"On the Role of Dietary Nitrate in the Maintenance of Systemic and Oral Health\",\"authors\":\"U. Schlagenhauf\",\"doi\":\"10.3390/dj10050084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The assessment of the significance of nitrates ingested with food has undergone a fundamental change in recent years after many controversial discussions. While for a long time, a diet as low in nitrates as possible was advocated on the basis of epidemiological data suggesting a cancer-promoting effect of nitrate-rich diets, more recent findings show that dietary nitrate, after its conversion to nitrite by nitrate-reducing bacteria of the oral microbiota, is an indispensable alternative source for the formation of nitric oxide (NO), which comprises a key element in the physiology of a variety of central body functions such as blood pressure control, defense against invading bacteria and maintenance of a eubiotic microbiota in the gut and oral cavity. This compact narrative review aims to present the evidence supported by clinical and in vitro studies on the ambivalent nature of dietary nitrates for general and oral health and to explain how the targeted adjuvant use of nitrate-rich diets could open new opportunities for a more cause-related control of caries and periodontal disease.\",\"PeriodicalId\":47284,\"journal\":{\"name\":\"Open Dentistry Journal\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2022-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Dentistry Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/dj10050084\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Dentistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/dj10050084","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 1

摘要

近年来,经过许多有争议的讨论,对食物中摄入硝酸盐的重要性的评估发生了根本性的变化。虽然长期以来,基于流行病学数据表明富含硝酸盐的饮食具有促进癌症的作用,人们提倡尽可能低硝酸盐的饮食,但最近的研究结果表明,饮食中的硝酸盐在被口腔微生物群中的硝酸盐还原细菌转化为亚硝酸盐后,是形成一氧化氮(NO)不可或缺的替代来源。它包含了多种中枢身体功能的生理学关键要素,如血压控制、抵御入侵细菌和维持肠道和口腔内的益生菌群。这篇紧凑的叙述性综述旨在提供临床和体外研究支持的证据,证明膳食硝酸盐对一般健康和口腔健康的矛盾性质,并解释如何有针对性地辅助使用富含硝酸盐的饮食可以为龋齿和牙周病的病因相关控制开辟新的机会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On the Role of Dietary Nitrate in the Maintenance of Systemic and Oral Health
The assessment of the significance of nitrates ingested with food has undergone a fundamental change in recent years after many controversial discussions. While for a long time, a diet as low in nitrates as possible was advocated on the basis of epidemiological data suggesting a cancer-promoting effect of nitrate-rich diets, more recent findings show that dietary nitrate, after its conversion to nitrite by nitrate-reducing bacteria of the oral microbiota, is an indispensable alternative source for the formation of nitric oxide (NO), which comprises a key element in the physiology of a variety of central body functions such as blood pressure control, defense against invading bacteria and maintenance of a eubiotic microbiota in the gut and oral cavity. This compact narrative review aims to present the evidence supported by clinical and in vitro studies on the ambivalent nature of dietary nitrates for general and oral health and to explain how the targeted adjuvant use of nitrate-rich diets could open new opportunities for a more cause-related control of caries and periodontal disease.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Open Dentistry Journal
Open Dentistry Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
2.00
自引率
0.00%
发文量
86
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信