{"title":"外泌体miRNA作为乳腺癌标志物的临床应用","authors":"Lixia Cao, Zhen-dong Shi, Jingjing Liu","doi":"10.3760/CMA.J.ISSN.1673-422X.2019.07.007","DOIUrl":null,"url":null,"abstract":"MicroRNA (miRNA) has a tumor-specific expression profile and plays an important role in the occurrence and progression of tumors. It is protected from RNase in body fluids through the inclusion of exosomes and translocates genetic information horizontally between breast cancer cells. Recent studies on exosome miRNA have found that it is closely related to the occurrence, diagnosis, treatment and prognosis of breast cancer. The in-depth study in this field can provide theoretical basis for the clinical application of exosome miRNA as a biomarker for breast cancer. \n \n \nKey words: \nBreast neoplasms; Exosomes; MicroRNAs; Biomarker","PeriodicalId":16120,"journal":{"name":"国际肿瘤学杂志","volume":"25 1","pages":"423-426"},"PeriodicalIF":0.0000,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical application of exosomal miRNA as biomarker in breast cancer\",\"authors\":\"Lixia Cao, Zhen-dong Shi, Jingjing Liu\",\"doi\":\"10.3760/CMA.J.ISSN.1673-422X.2019.07.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"MicroRNA (miRNA) has a tumor-specific expression profile and plays an important role in the occurrence and progression of tumors. It is protected from RNase in body fluids through the inclusion of exosomes and translocates genetic information horizontally between breast cancer cells. Recent studies on exosome miRNA have found that it is closely related to the occurrence, diagnosis, treatment and prognosis of breast cancer. The in-depth study in this field can provide theoretical basis for the clinical application of exosome miRNA as a biomarker for breast cancer. \\n \\n \\nKey words: \\nBreast neoplasms; Exosomes; MicroRNAs; Biomarker\",\"PeriodicalId\":16120,\"journal\":{\"name\":\"国际肿瘤学杂志\",\"volume\":\"25 1\",\"pages\":\"423-426\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"国际肿瘤学杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-422X.2019.07.007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"国际肿瘤学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-422X.2019.07.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Clinical application of exosomal miRNA as biomarker in breast cancer
MicroRNA (miRNA) has a tumor-specific expression profile and plays an important role in the occurrence and progression of tumors. It is protected from RNase in body fluids through the inclusion of exosomes and translocates genetic information horizontally between breast cancer cells. Recent studies on exosome miRNA have found that it is closely related to the occurrence, diagnosis, treatment and prognosis of breast cancer. The in-depth study in this field can provide theoretical basis for the clinical application of exosome miRNA as a biomarker for breast cancer.
Key words:
Breast neoplasms; Exosomes; MicroRNAs; Biomarker
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
