产前贫血与非贫血常规补铁孕妇出生体重的比较

T. Atakul
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摘要

目的:探讨在妊娠期常规补铁的孕妇中,产前血液学参数对出生体重的影响,并比较其与产妇年龄和胎次的关系。研究设计:对足月分娩的低风险孕妇进行回顾性研究。从患者档案中提取出产前血液学参数和临床信息,并与出生体重进行比较。已知有血液病的妇女、有静脉补铁治疗史的妇女和不经常补铁的妇女被排除在外。结果:所有患者(1066例)均在分娩前进行了全血检查。血红蛋白、红细胞压积、平均红细胞体积、红细胞计数和红细胞分布宽度的平均值为:10.9 g / dL(±1.4),34.6%(±4.3),84.6(±7.8),4.1 g / dL(±0.4),分别为和14.2%(±2.5)。当对所有患者进行评估时,其中300人(28%)根据世界卫生组织的标准被发现贫血,但不符合以前的ACOG临界值(9.5 g/dL)。产前贫血和出生体重之间没有明显的联系。然而,根据这两个标准,发现贫血妇女组比非贫血妇女组略年轻。结论:我们的研究结果表明,年龄越小,分娩前贫血越明显。这项研究没有显示出产前贫血和低出生体重之间的任何联系,与母亲的年龄无关。需要进一步研究妊娠期间血红蛋白降低对特定年龄组婴儿出生体重和胎盘功能不全相关疾病的预后重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Birth Weights of Pre-Delivery Anemic and Non-Anemic Routine Iron Supplemented Pregnant Women
OBJECTIVE: To investigate the effects of pre-delivery hematological parameters on birth weight and to compare their relationship with maternal age and parity in women who had taken routine iron supplementation during pregnancy STUDY DESIGN: A retrospective study was conducted among low-risk pregnant women who were delivered at term. Pre-delivery hematological parameters and clinical information were extracted from patient files and compared with birth weights. Women with known hematological disorders, women with the previous history of intravenous iron treatment and the ones who did not regularly use iron supplementation were excluded. RESULTS: All patients (1066) had undergone complete blood testing before delivery. Mean values for hemoglobin, hematocrit, mean corpuscular volume, red blood cell count and red cell distribution width were as follows; 10.9g/dL (±1.4), 34.6 % (±4.3), 84.6fL (±7.8), 4.1g/dL (±0.4), and 14.2 % (±2.5), respectively. When all patients are evaluated, 300 (28%) of them were found to be anemic according to Word Health Organization criteria but not for the former ACOG cut-off, which was 9.5 g/dL. There was no significant association between pre-delivery anemia and birth weight. However, the anemic women group was found to be slightly younger than non-anemic ones according to both criteria. CONCLUSION: Our results documented that younger age was associated with more pronounced anemia before delivery. This study did not show any association between pre-delivery anemia and low birth weight irrespective of maternal age. There is a need for further reports investigating the prognostic importance of hemoglobin reduction during pregnancy for infant birth weight in specific age groups and placental insufficiency related conditions.
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