在比得哥什肿瘤中心接受治疗的乳腺癌患者的总生存期和无病生存期——超过六年的随访分析

T. Nowikiewicz, M. Wiśniewska, Michał Wiśniewski, M. Biedka, I. Głowacka, D. Kozak, R. Laskowski, W. Zegarski
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引用次数: 6

摘要

研究目的乳腺恶性肿瘤是发达国家最大的肿瘤问题。近年来,每年新诊断的病例超过16500例。考虑到全国各省的情况,关于乳腺癌治疗的遥远结果的公布数据可能不能代表特定肿瘤中心取得的治疗效果。本文的目的是分析2006年在比得哥什肿瘤中心治疗的乳腺癌患者的远程治疗结果。他们与库贾维斯科-波莫尔斯基省和全波兰的数据进行了比较。材料与方法对2006年1月1日至12月31日在Bydgoszcz肿瘤中心就诊的667例乳腺癌患者进行队列研究。根据TNM分期系统,研究组以I期(26.2%)和II期(48.3%)患者居多,III期占17.5%,IV期占6.4%。计算5年生存率和5年无病生存率。中位观察时间为79个月。结果148例患者复发,占22.2%。168例(25.2%)死于原发疾病。5年生存率为0.761±0.017,5年无病生存率为0.807±0.016。中位生存期为76.4个月,中位无病生存期为19.4个月。结论在Bydgoszcz肿瘤中心接受治疗的乳腺癌患者5年生存率高于全波兰5年生存率中位数。观察需要继续进行,并应包括在随后的时间段对治疗的评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Overall survival and disease-free survival in breast cancer patients treated at the Oncology Centre in Bydgoszcz – analysis of more than six years of follow-up
Aim of the study Malignant breast tumours are the largest oncological problem in the developed world. In the recent years the number of new diagnoses has exceeded 16,500 per year. Published data regarding far-distant results of breast cancer treatment that take under consideration the provincial division of the country may not be representative of the therapeutic effects achieved in specific oncological centres. The goal of this article is to analyse far-distant therapeutic results in breast cancer patients treated at the Oncology Centre in Bydgoszcz in 2006. They were compared with data available for Kujawsko-Pomorskie Voivodeship and with all-Poland results. Material and methods A cohort of 667 breast cancer patients at Bydgoszcz Oncology Centre between Jan 1 and Dec 31, 2006 was studied. The majority of the studied group were patients in stage I (26.2%) and II (48.3%) according to the TNM staging system, 17.5% were in stage III, and 6.4% in stage IV. The 5-year survival and 5-year disease-free survival rates were calculated. Median observation time was 79 months. Results A total of 148 patients (22.2%) suffered a relapse. There were 168 (25.2%) deaths caused by primary disease. The 5-year survival probability was 0.761 ±0.017 and the five-year disease-free survival probability was 0.807 ±0.016. Median survival time was 76.4 months, and median disease-free survival was 19.4 months. Conclusions The five-year survival probability for breast cancer patients undergoing treatment at Bydgoszcz Oncology Centre was higher than all-Poland median five-year survival probability. The observation needs to be continued and should include the assessment of treatment in subsequent time periods.
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