用于识别癌细胞侵袭性等级的微波生物传感器

Ling Yan Zhang, Christophe Bounaix Morand du Puch, A. Lacroix, C. Dalmay, A. Pothier, C. Lautrette, S. Battu, F. Lalloué, M. Jauberteau, P. Blondy
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引用次数: 28

摘要

本文阐述了微波频率在生物分析中的潜力。一旦进入生物细胞,微波可以与细胞内的内容物相互作用,并告知其安全或恶性状态。这项工作表明,他们的癌症等级(即侵袭性水平)也可以通过这种方式来确定。因此,基于负载RF谐振器的三种结肠癌细胞系的介电常数测量,所提出的结果显示,在所分析细胞的癌症等级中,电磁特征存在显着差异。这种传感方法很有希望为早期癌症诊断开发新的有力工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microwave biosensors for identifying cancer cell aggressiveness grade
This paper illustrates the potential of microwave frequencies for biological analysis. Once penetrating inside biological cells, microwaves can interact with their intracellular content and inform on their safe or malignant state. This work demonstrates that their cancer grade (i.e. aggressiveness level) can also be identified by this way. Hence, based on permittivity measurements on three colon cancer cell lines loading RF resonators, the presented results show significant differences of electromagnetic signature in the cancer grade of analyzed cells. This sensing method appears very promising to develop new powerful tools for early cancer diagnostic.
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