牛血清白蛋白单体在不同酸碱值pH的水分散体中聚集的研究

2018 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus) Pub Date : 2018-01-01 DOI:10.1109/EICONRUS.2018.8317480

B. A. Kvasnov, P. Shalaev, S. Dolgushin

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引用次数: 3

摘要

采用动态光散射法和电泳光散射法对不同酸碱值pH的牛血清白蛋白水溶液分散体样品进行了研究。测定了白蛋白单体、小聚集体和大聚集体的水动力直径以及样品的zeta电位。得到了白蛋白聚集体的水动力直径和zeta电位与溶液中蛋白质浓度和白蛋白水分散体pH的关系。

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Study of the aggregation of bovine serum albumin monomers in aqueous dispersions with different acid-base value pH

Samples of aqueous dispersions of bovine serum albumin with different acid-base value pH were studied using dynamic light scattering and electrophoretic light scattering methods. The hydrodynamic diameter of monomers, small aggregates and large aggregates of albumin and the zeta potential of the samples were measured. Dependencies of the hydrodynamic diameter and the zeta potential of albumin aggregates on the protein concentration in solution and pH of the aqueous dispersion of albumin were obtained.

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2018 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus)

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