某多专科医疗机构员工COVID-19表现流行过程及Gam-Covid-Vac疫苗流行病学疗效评估

V. I. Sergevnin, S. M. Ratnikova, N. G. Zueva, M. V. Rozhkova
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引用次数: 1

摘要

的相关性。医疗机构的员工由于其公务性质,处于新型冠状病毒感染发病的群体风险中。某多专科医疗机构员工COVID-19流行过程表现及使用Gam-Covid-Vac疫苗的流行病学效果评价材料和方法。对2020年3月至2021年12月MO工作人员COVID-19的发病率进行了研究。根据员工常规血清学检测SARS-CoV-2抗体IgM和IgG的结果,评估潜伏流行过程。通过比较完成疫苗接种过程的员工的发病率和覆盖率来确定免疫预防的流行病学有效性。在研究期间,47.7%的医疗机构员工有临床明显的COVID-19形式。此外,根据常规血清学检查的结果,46.5%的员工有亚临床感染。在秋季观察到发病率增加。医务工作者的发病率比其他职工高2.2倍,医院医务人员的发病率比综合诊所高1.7倍。护士组的流行过程比医生和初级医务人员更强烈。已确定Gam-Covid-Vac在使用疫苗的头几个月内的流行病学效力。与未接种疫苗的人相比,接种疫苗的人的病程更轻。通过此方法,确定了某多专科医疗机构员工COVID-19流行过程的主要表现,并确定了Gam-Covid-Vac疫苗在使用前几个月的流行病学有效性
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of the Epidemic Process of COVID-19 Manifestations and the Epidemiological Efficacy of the Vaccine Gam-Covid-Vac Among Employees of a Multi-Speciality Medical Organization
Relevance. Employees of medical organizations (MO), by virtue of their official duties, are at the group risk of morbidity of a new coronavirus infection.Aim. Evaluation of the manifestations of the COVID-19 epidemic process and the epidemiological effectiveness of the use of the Gam-Covid-Vac vaccine among employees of a multy-speciality medical organization.Materials and methods. The incidence of COVID-19 among the staff of MO was studied for the period from March 2020 to December 2021. The latent epidemic process was evaluated avccording to the results of routine serological examination of employees for antibodies of classes IgM and IgG to SARS-CoV-2. The epidemiological effectiveness of immunoprevention was determined by comparing the incidence with the coverage of employees who has a completed course of vaccination.Results. During the study period, 47.7% of employees of medical organizations had a clinically apparent form of COVID-19. In addition, according to the results of a routine serological examination, it turned out that 46.5% of employees had a subclinical form of infection. An increased level of morbidity was observed in the autumn period. The incidence of medical workers was in 2.2 times higher than other employees, medical staff of the hospital – in 1.7 times higher than polyclinics. The epidemic process was more intense in the group of nurses than doctors and junior medical staff. The epidemiological efficacy of the Gam-Covid-Vac during the first months of using vaccine has been established. Vaccinated people have a more mild course of COVID-19 in comparison with unvaccinated people.Conclusion. In this way, the main manifestations of the COVID-19 epidemic process in employees of a multy-speciality medical organization were identified and the epidemiological effectiveness of the Gam-Covid-Vac vaccine in the first months of using vaccine was established
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