模拟子宫颈癌对放射治疗的反应

Christos A. Kyroudis, D. Dionysiou, E. Kolokotroni, Jesper F. Kallehague, K. Tanderup, G. Stamatakos
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引用次数: 1

摘要

本文的目的是介绍在DrTherapat项目(FP7-ICT-600852)背景下开发的宫颈癌onco模拟器(CERONCO)模拟模块的基本科学原理和核心算法。CERONCO模拟了宫颈肿瘤在患者个体化背景下对放射治疗(外束放疗后近距离放疗)和每周顺铂治疗的反应。基于一个临床病例的磁共振成像数据的初步临床适应性研究结果也被提出。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simulation of cervical cancer response to radiotherapy
The goal of this article is to present basic scientific principles and core algorithms of the simulation module of the CERvical cancer ONCOsimulator (CERONCO) developed within the context of the DrTherapat project (FP7-ICT-600852). CERONCO simulates the response of cervical tumours to radiotherapy treatment (external beam radiotherapy followed by brachytherapy) with concomitant weekly cisplatin, in the patient-individualized context. Results from a preliminary clinical adaptation study based on the MR imaging data of a clinical case are presented as well.
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