糖化血红蛋白在糖尿病COVID-19患者中的不良预后因素

E. Torun Parmaksız, E. Parmaksız
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引用次数: 0

摘要

背景:糖尿病(DM)似乎增加了冠状病毒病-2019 (COVID-19)的风险。我们的目的是评估血糖控制对糖尿病COVID-19患者患病率和死亡率的影响。材料与方法:回顾性观察研究收集2020年3月至2021年3月在我院诊断为COVID-19的糖尿病患者的资料。记录患者的人口学、临床、实验室和放射学资料以及治疗过程和结果。结果:352例糖尿病患者与333例非糖尿病对照进行对比。男性184例,女性168例,平均年龄63.7±13.0(30-91岁)。与非糖尿病人群相比,糖尿病人群的住院时间、重症监护病房(ICU)入院率和死亡率更高。HbA1c高于7%组的ICU住院率和死亡率明显高于对照组。结论:未控制的糖尿病是导致SARS-CoV-2感染严重程度的有害合并症之一,良好的血糖水平控制将改善COVID-19患者的预后。血糖控制较差的糖尿病人群更易感染COVID-19。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Glycolyzed hemoglobin as a poor prognostic factor in diabetic COVID-19 patients
Background: Diabetes mellitus (DM) seems to be conveying increased risk in Coronavirus disease-2019 (COVID-19). We aimed to evaluate the effect of glycemic control on the risk of prevalence and mortality in diabetic COVID-19 patients. Materials and Methods: In this retrospective observational study, the data from diabetic patients admitted to our hospital with the diagnosis of COVID-19 between March 2020 and March 2021 were reviewed. The demographic, clinical, laboratory, and radiological data, and the course and outcomes were recorded. Results: The records of 352 diabetic patients were compared to 333 non-diabetic controls. The mean age of 184 male and 168 female patients was 63.7±13.0 (30–91). The length of hospital stay, rate of Intensive care unit (ICU) admission, and mortality were higher in the diabetic population compared to the non-diabetic counterparts. ICU admission and mortality rates were significantly higher in the group with HbA1c higher than 7%. The rate of ICU admission and mortality was significantly higher in participants with elevated HbA1cConclusions: Uncontrolled DM is among detrimental comorbidities contributing to the severity of SARS-CoV-2 infection and good control of serum glucose levels will improve prognosis in COVID-19. The diabetic population with poor glycemic control succumbed more to COVID-19.
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