黏液纤维肉瘤样多形性脂肪肉瘤

IF 0.1 Q4 PATHOLOGY
D. Hariri, A. Benyounes, Derik L Davis, M. Mulligan, V. Ng, M. Kallen
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引用次数: 0

摘要

多形性脂肪肉瘤是脂肪肉瘤中最不常见的亚型,占不到5%的病例,但由于多形性脂肪肉瘤的预后更差,更接近于高级别肉瘤,因此与其他脂肪肉瘤亚型区分是很重要的。除了诊断性多形性脂肪母细胞外,相当比例的病例表现出与黏液纤维肉瘤重叠的组织学特征。与其他类型的脂肪肉瘤相比,这些脂肪母细胞对多形性脂肪肉瘤的诊断至关重要,但在范围上可能是高度局灶性的/可变的,需要广泛的大体取样和彻底的组织学检查,特别是在小活检中,这是诊断的一个陷阱。意识到这种不常见的组织模式将有助于正确诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Myxofibrosarcoma-Like Pleomorphic Liposarcoma
Abstract Pleomorphic liposarcoma is the least common subtype of liposarcoma, accounting for less than 5% of cases, but is important to distinguish from other liposarcoma subtypes due to a significantly worse prognosis closer to that of a high-grade sarcoma. A substantial proportion of cases demonstrate histologic features overlapping with myxofibrosarcoma, except for the presence of diagnostic pleomorphic lipoblasts. These lipoblasts are essential to the diagnosis of pleomorphic liposarcoma, in contrast to the other subtypes of liposarcoma, but can be highly focal/variable in extent, mandating extensive gross sampling and thorough histologic examination and representing a pitfall in diagnosis particularly in small biopsies. Awareness of the less common histologic patterns of this uncommon entity will hopefully facilitate correct diagnosis.
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CiteScore
0.30
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