青光眼局部降低眼压的机会

IF 1.7 4区管理学 Q3 OPERATIONS RESEARCH & MANAGEMENT SCIENCE

4or-A Quarterly Journal of Operations Research Pub Date : 2021-03-13 DOI:10.9734/OR/2021/V14I230189

O. Rahić, A. Tucak, M. Sirbubalo, Lamija Hindija, J. Hadžiabdić, E. Vranić

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引用次数: 1

摘要

由于青光眼是一种严重的健康问题，许多治疗方法正在开发，以降低眼压(IOP)作为唯一可改变的因素，所有青光眼症状。将降血压药物分为六类，每一类药物都有特定的作用机制和副作用，这是本文的重点，并对其进行了详细的说明。上述所有药剂均配制为滴眼液。然而，由于传统的局部滴眼液具有明显的缺点，主要是生物利用度差和患者不依从性，因此本文采用了新的方法来设计其给药系统，并在本文中简要介绍。rahiki et al.;Or, 14(2): 17- 33,2021;文章no.OR。6619718图形摘要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Opportunities to Topically Reduce Intraocular Pressure in Glaucoma

Since glaucoma is a serious health problem, numerous therapeutics are being developed to reduce Intraocular Pressure (IOP) as the only modifiable factor of all glaucoma symptoms. IOP-lowering agents are divided into six groups, each of which has a specific mechanism of action and side effects, which are the focus of this article and are explained in detail. All the mentioned agents are formulated as eye drops. However, as conventional topical eye drops have significant disadvantages, of which poor bioavailability and patient noncompliance are the main, novel approaches to designing their drug delivery systems were used and briefly presented in this review. Review Article Rahić et al.; OR, 14(2): 17-33, 2021; Article no.OR.66197 18 Graphical Abstract

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来源期刊

4or-A Quarterly Journal of Operations Research 管理科学-运筹学与管理科学

CiteScore

3.80

自引率

5.00%

发文量

审稿时长

6 months

期刊介绍： 4OR - A Quarterly Journal of Operations Research is jointly published by the Belgian, French and Italian Operations Research Societies. It publishes high quality scientific papers on the theory and applications of Operations Research. It is distributed to all individual members of the participating societies.