泰国有骨水泥和无骨水泥牛津单腔膝关节置换术的并发症、再手术原因和5年假体存活率比较

Q4 Medicine
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摘要

背景:牛津单室膝关节置换术(OUKA)对内侧室性膝骨关节炎患者疗效良好。然而,在亚洲人群中,骨水泥或无骨水泥的OUKA固定是否能提供更好的治疗效果尚不清楚。目的:比较泰国有骨水泥与无骨水泥OUKA患者的并发症、再手术原因及5年假体生存率。材料和方法:在2011年至2015年期间进行了466例胶结和36例无胶结OUKA,随访时间至少为5年。以任何原因再次手术为终点,Kaplan-Meier分析比较两组间5年种植体存活率。比较两组患者并发症、再手术原因及90天病死率。采用Cox比例风险模型确定种植体存活的独立预测因素。结果:骨水泥组与无骨水泥组的5年种植体存活率差异无统计学意义,分别为96.4%和94.4% (p=0.375)。骨水泥组和无骨水泥组种植体平均存活时间分别为113.0±0.8个月和70.8±1.9个月(p=0.383)。再手术最常见的原因是轴承脱位,只有1例患者90天发病。两组间并发症及再手术原因无明显差异。在多变量分析中没有发现种植体存活的独立预测因素。结论:OUKA被证明是一种安全、持久的泰国内侧室性膝关节骨关节炎重建手术。在5年的随访中,骨水泥组和非骨水泥组的种植体存活率没有显著差异,也没有发现独立的预测种植体存活率的因素。试验注册:泰国临床试验注册中心,TCTR20200427004,注册日期为2020年4月27日,回顾性注册。再次手术的原因;5年种植体存活;牛津单腔膝关节置换术(OUKA);泰国
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complications, Reasons for Reoperation, and 5-Year Prosthesis Survival Compared between the Cemented and Cementless Oxford Unicompartmental Knee Arthroplasty in Thai Patients
Background: Oxford unicompartmental knee arthroplasty (OUKA) yields favorable outcomes in patients with medial compartmental knee osteoarthritis. However, it remains unknown whether cemented or cementless OUKA fixation delivers better outcomes in Asian population. Objective: To investigate the complications, reasons for reoperation, and 5-year prosthesis survival compared between cemented and cementless OUKA in Thai patients. Materials and Methods: Four hundred sixty-six cemented and 36 cementless OUKA performed between 2011 and 2015 with a minimum follow-up of five years were included. With reoperation for any reason as the endpoint, Kaplan-Meier analysis was performed to compare 5-year implant survival between groups. Complications, reasons for reoperation, and 90-day morbidity and mortality were compared between groups. Cox proportional hazards model was used to identify independent predictors of implant survival. Results: There was no significant difference in 5-year implant survival between the cemented and the cementless groups at 96.4% versus 94.4% (p=0.375). The mean implant survival time was 113.0±0.8 and 70.8±1.9 months in the cemented and the cementless groups, respectively (p=0.383). The most common reason for reoperation was bearing dislocation, and only one patient had 90-day morbidity. There was no significant difference between groups for complications or reasons for reoperation. No independent predictors of implant survival were identified in multivariate analysis. Conclusion: OUKA was shown to be a safe and durable reconstructive procedure in Thai patients with medial compartmental knee osteoarthritis. There was no significant difference in implant survival between the cemented and the cementless groups during the 5-year follow-up, and no independent predictors of implant survival were identified. Trial registration: Thai Clinical Trials Registry, TCTR20200427004, registered 27 April 2020, retrospectively registered Keywords: Complications; Reasons for reoperation; 5-year implant survival; Oxford unicompartmental knee arthroplasty (OUKA); Thailand
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