兰科的成员林德尔。作为药用植物原料的来源,可获得嗜神经药物

Е. V. Zvezdina, J. V. Dayronas, I. Bochkareva, I. N. Zilfikarov, E. Babaeva, E. V. Ferubko, Z. Guseynova, Фатима Казбековна Серебряная, S. R. Kaibova, T. Ibragimov
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引用次数: 6

摘要

本文综述和分析了现代科学文献中对Lamiaceae科植物的生物活性物质、药用物质、总提取物和具有神经活性的药物的药理学、生药学和药理学研究的资料。材料和方法。为了进行综述,我们使用了近20年来来自各机构科技图书馆和电子数据库(图书馆、PubMed、Scopus、Cyberleninka、GoogleAcademy、J-Stage)中开放和可访问资源的科学文献信息。检索查询的内容为:兰科植物种类(俄文和拉丁文)、以其为原料的药用植物样品、从这些原料中提取的药物和生物活性物质的名称。在处理科学信息来源时,主要关注的是在实验动物研究期间进行的药理学测试,并证明在研究对象中存在嗜神经活性——精油和植物原料提取物:含水、含水酒精和甲醇。从紫唇科30个属的药用植物材料中提取的药用物质和药物在治疗和预防方面的应用潜力尚未得到充分的认识。本文综述了30属71种。尽管在本出版物的分析中提出了先前研究的重要水平,但该家族物种的巨大潜力仍未被探索。在未来,它们可以同时具有生药学和实用价值,特别是在创造基于它们的嗜神经作用的新药物制剂方面。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Members of the family Lamiaceae Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs
The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them.
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