K. Doneva-Basheva, D. Petrov, T. Vlaykova, S. Tisheva
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引用次数: 0
摘要
心血管疾病(CVD)是发达国家致残和死亡的主要原因。其中,死亡的主要原因是冠状动脉疾病。在这项回顾性研究中,纳入172例急性冠状动脉综合征(STEMI, NSTEMI, UA)患者。2009年1月至2010年2月期间,他们曾在斯塔拉扎戈拉的St. Kirkovich教授医院的心脏病科、侵入科和扬博尔心脏病医院急诊住院。我们发现急性冠脉综合征(ACS)发生的年龄在性别上有显著差异:男性表现较早(p=0.018)。单变量回归分析显示,老年人年龄(p=0.005, OR 1.024)、肾小球滤过140 pt (p= 140 p。
Predictors for Long-Term Prognosis after Acute Coronary Syndrome
Summary Cardiovascular diseases (CVD) are the leading cause of invalidity and death in developed countries. Among them, the main cause of death is coronary artery disease. In this retrospective study, 172 patients with acute coronary syndrome (STEMI, NSTEMI, UA) are included. They had been hospitalized on an emergency basis in the Cardiology Department, Invasive Sector of Prof. Dr. St. Kirkovich Hospital in Stara Zagora, and the Cardiology Hospital -Yambol between January 2009 and February 2010. We found a significant difference in the age at acute coronary syndrome (ACS) occurrence by sex: earlier manifestation was observed in men (p=0.018). The univariant regression analysis showed that elderly age (p=0.005, OR 1.024), glomerular filtration <90 ml/h (p=0.006, OR 0.964), GRACE-score > 140 pt (p<0.001, OR 1.045), HF (Killip class ≥ II) (p=0.002, OR 15.6) and EF<40% (p=0.003, OR 1) were factors for adverse prognosis in the first, fifth and ninth year. Only GRACE-score was an independent predictor of death obtained by multivariate regression analysis in the study (p=0.002, OR 1.052). The factors influencing long-term survival adversely after ACS are age, smoking, chronic kidney disease, previously experienced myocardial infarction, diabetes mellitus, three-vessel coronary disease, and decreased systolic function of the left ventricle, and GRACE > 140 p.