{"title":"微波诱导合成对映纯β-内酰胺","authors":"B. Indrani, Fredrick Fb, Bimal Kb","doi":"10.4172/2329-6798.1000228","DOIUrl":null,"url":null,"abstract":"Synthesis of enantiopure C-3/C-4 disubstituted β-lactams has been achieved through Staudinger cycloaddition reaction of acid chloride and imine under microwave irradiation. Importantly, reactions has been manipulated by proper selection of substrates to obtain both enantiomers in high yield.","PeriodicalId":18605,"journal":{"name":"Modern Chemistry & Applications","volume":"9 1","pages":"1-3"},"PeriodicalIF":0.0000,"publicationDate":"2017-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Microwave-Induced Synthesis of Enantiopure β- Lactams\",\"authors\":\"B. Indrani, Fredrick Fb, Bimal Kb\",\"doi\":\"10.4172/2329-6798.1000228\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Synthesis of enantiopure C-3/C-4 disubstituted β-lactams has been achieved through Staudinger cycloaddition reaction of acid chloride and imine under microwave irradiation. Importantly, reactions has been manipulated by proper selection of substrates to obtain both enantiomers in high yield.\",\"PeriodicalId\":18605,\"journal\":{\"name\":\"Modern Chemistry & Applications\",\"volume\":\"9 1\",\"pages\":\"1-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Modern Chemistry & Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2329-6798.1000228\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Modern Chemistry & Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2329-6798.1000228","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Microwave-Induced Synthesis of Enantiopure β- Lactams
Synthesis of enantiopure C-3/C-4 disubstituted β-lactams has been achieved through Staudinger cycloaddition reaction of acid chloride and imine under microwave irradiation. Importantly, reactions has been manipulated by proper selection of substrates to obtain both enantiomers in high yield.
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