Effects of exercise prescription on quality of life in patients with pituitary adenomas after surgery

Objective To investigate the effects of exercise prescription on quality of life in patients with pituitary adenomas after surgery. Methods A total of 82 patients with pituitary adenomas who met the inclusion criteria from December 2017 to September 2018 were enrolled. The control group received routine nursing care. The intervention group was given exercise prescription on the first day after surgery and 3 months after discharge from hospital. Both groups of patients completed the Health Status Survey(SF-36) before and after the intervention. Results Before the intervention, there was no significant difference in baseline date of patients between two groups(P>0.05). After intervention, the general health dimension score (53.03±11.30) of the control group was significantly higher than the score within the group before treatment (Z value was -4.398, P<0.05). The physiological function (86.67±7.46), physical function (66.67±29.28), role-emotional (71.30±22.75), vitality (68.33±8.78), general health dimension (61.39±10.66) of the intervention group were significant higher than the score within the group before treatment (Z values were -4.809--2.041, P<0.05) . After the intervention, the significant difference were found in role-physical, general health, vitality, social function(77.18±15.71) and physiological health dimensions (73.75±10.00) between the intervention and control group (Z values were -3.122- -2.467, t value was 3.044, P<0.05). After the intervention, non-function patients′ physiological function (72.06±23.19), general health (60.59±10.75), vitality (69.71±10.23) and social function (81.04±10.22) were significantly higher than the control group (Z values were -2.832- -2.059, P<0.05). Conclusion Exercise prescription can improve the quality of life in patients with pituitary adenomas after surgery. Key words: Pituitary neoplasms; Exercise; Rehabilitation nursing; Quality of life