Healing Mechanism Surrounding Transplanted Bone Using Transgenic Mice Expressing Red Fluorescent Protein in Vivo

74 INTRODUCTION Dental implants have become an essential treatment method for edentulous patients, and the number of clinical cases employing dental implants have been increasing all over the world at least past 10 years . However, implant therapy is not applicable for all the patients due to insufficient bone mass or an individual’s general condition. To induce or regenerate newly formed bone in an area with defective or lost bone tissue, various bone augmentation techniques have been applied. Various types of bone substitutes have been developed to support bone augmentation; however, the autogenous bone graft is still regarded as the gold standard. Autogenous bone is the only graft material that has osteogenic properties and fulfills all three components of the regeneration triangle (cells, scaffolds, Healing Mechanism Surrounding Transplanted Bone Using Transgenic Mice Expressing Red Fluorescent Protein in Vivo