睡眠时癫痫样放电和癫痫发作时昼夜节律调节的回顾研究

IF 0.6 Q3 Medicine
Sujithra Srinivas
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引用次数: 0

摘要

癫痫是一种影响全球约5000多万人的神经系统疾病,其中发达国家也可见该病的流行。癫痫的临床定义为两次或两次以上的非触发性癫痫发作。癫痫发作可以被描述为一种发作性事件,它是由神经元的高度同步引起的,有各种各样的表现原因。神经元放电可能局限于特定的大脑皮层,也可能广泛分布于整个大脑皮层。脑电图(EEG)用于癫痫的诊断和治疗,可用于常规检查,也被认为是癫痫综合征调查的金标准。在脑电图中,癫痫样间歇放电的分布、存在和频率提示癫痫的诊断。换句话说,个人脑电图中出现的ied是癫痫的诊断。在睡眠期间进行的脑电图中主要发现ied,可以对睡眠相关性癫痫患者进行基本的诊断和预后。在睡眠期间,潜伏的间歇放电被激活。睡眠简易爆炸装置据说对癫痫的控制有很大的影响。这些睡眠和癫痫的相互作用机制往往会导致癫痫发作行为的改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Review study on epileptiform discharge during sleep and circadian rhythm modulation during seizures
Epilepsy is a neurological condition that affects approximately more than 50 million people around the globe, out of which the prevalence of this disease is also seen in developed countries. Epilepsy can be clinical defined by two or more non triggered seizures. A seizure can be characterized as a paroxysmal event which is caused due to hyper–synchronization in the neurons that many have various reasons of manifestation. The neuronal discharge maybe focal spreading in specific brain cortex or widespread throughout the cortex. An Electroencephalogram (EEG) is used to in diagnosis and management of epilepsy and can be used for routine examinations, it also considered to be the golden standard investigation of epileptic syndrome. While using EEG the distribution, presence and frequency of interictal epileptiform discharges IEDs are suggestive diagnosis of epilepsy. In other words the presence of IEDs in an individual’s EEG is a diagnosis of epilepsy. IEDs are predominantly found in EEG that is performed during sleep which can give basic diagnosis and prognosis of sleep related epilepsies in patients. During sleep latent interictal discharge are activated. Sleep IEDs are said to greatly affect the epilepsy management. These interaction mechanisms of sleep and epilepsies tends to bring about changes in behaviour of the seizure.
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来源期刊
CiteScore
0.90
自引率
0.00%
发文量
226
审稿时长
3 months
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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