Clinical And Radiographic Assessment of Xenogenic Bone Graft with or Without Hyaluronic Acid for Post Extraction Socket Preservation (Randomized Clinical Trial)

Aim: hyaluronic acid shows osteogenic potentials which considered important property during bone regeneration. So, we aim to assess the efficiency of hyaluronic acid with xenograft mixture in post extraction alveolar sockets to decelerate resorption of dental alveolar ridge. Materials and Methods: A total of twelve patients with twenty nonrestorable maxillary premolars, which were extracted atraumatically are included in this study. Twenty extracted sockets were divided randomly into two equal groups. Sockets were grafted as follows: Group (I) sockets were grafted by xenograft mixed with hyaluronic acid; Group (II) sockets were grafted by xenograft alone. CBCT scans are made for each patient to measure bone density while pain assessment was done by VAS (visual analogue scale) for pain postoperatively. Results: All preserved sockets enrolled in this study received final crowns over the abutments and the Osseo integrated implants were in fully function position without any complication. According to VAS pain recorded a higher mean value (7.4±1.35) for Group (I), in comparison to Group (II) (4.2±1.48). The differences between study and control groups were statistically significant (p=0.00). While Radiographic bone density Group (I) recorded a higher mean value (879.09±118.76), in comparison to Group (II) (546.18±123.61). The differences between study and control groups were statistically significant (p=0.00) Conclusion: The results clearly concluded that both groups are successful in achieving clinical and radiographic socket preservation with superiority for xenograft mixed with hyaluronic acid