肺间质驻留记忆CD8+ T细胞维持一线上皮记忆

The Tokushima journal of experimental medicine Pub Date : 2019-09-26 DOI:10.1084/jem.20190557

S. Takamura, Shigeki Kato, Chihiro Motozono, T. Shimaoka, S. Ueha, K. Matsuo, Kosuke Miyauchi, Tomoko Masumoto, Asami Katsushima, T. Nakayama, M. Tomura, K. Matsushima, M. Kubo, M. Miyazawa

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引用次数: 49

摘要

肺间质和气道中的组织驻留肺记忆CD8+ TRM细胞与TEM细胞隔区分离，肺气道TRM细胞主要通过肺间质细胞的连续播散来维持。

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Interstitial-resident memory CD8+ T cells sustain frontline epithelial memory in the lung

Tissue-resident lung memory CD8+ TRM cells in the lung interstitium and airways are compartmentally separated from TEM cells, and lung airway TRM cells are primarily maintained by the continuous seeding of cells from the lung interstitium.

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The Tokushima journal of experimental medicine

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