姜黄和黑孜然在大鼠模型中的降血糖和降血脂潜能

IF 0.7 4区农林科学 Q3 AGRICULTURE, MULTIDISCIPLINARY

Pesquisa Agropecuaria Brasileira Pub Date : 2022-01-01 DOI:10.19045/BSPAB.2022.110013

S. Mobeen

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引用次数: 0

摘要

糖尿病(DM)是一种扰乱人体代谢过程的复杂疾病，在世界范围内普遍存在。在全球范围内，天然产物在纠正糖尿病及其相关水平方面得到了广泛的重视。本研究旨在探索姜黄和黑孜然的治疗潜力，以减少与饮食有关的功能失调，如糖尿病，这是由血糖水平升高引起的。姜黄和黑孜然都具有预防疾病的特性，如抗糖尿病、抗高脂血症、抗氧化剂和许多其他物质。通过对链脲佐菌素诱导的糖尿病大鼠的疗效研究，评价姜黄和黑孜然的治疗作用。将大鼠分为5组，G0为健康大鼠，G1为未给予任何治疗的糖尿病大鼠，G2为给予姜黄粉治疗的糖尿病大鼠，G3为给予黑孜然粉治疗的糖尿病大鼠，G4为给予姜黄粉和黑粉联合治疗的糖尿病大鼠。本研究的目的是评估姜黄和黑孜然对大鼠的抗糖尿病作用。结果表明，姜黄与黑孜然合剂对大鼠血糖水平和血脂水平的改善作用明显优于单用姜黄与黑孜然。由此可见，姜黄和黑孜然具有治疗糖尿病及相关疾病的潜力。

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Hypoglycemic and hypolipidemic potential of turmeric and black cumin in rat model

Diabetes Mellitus (DM) is a complex ailment that disturb metabolic process of body and prevalent worldwide. Natural products have gained substantial consideration in correcting diabetes and its associated level globally. This research is conducted to access the therapeutic potential of turmeric and black cumin to lessen the diet related malfunctioning like diabetes mellitus which is defined by elevated blood glucose level. Turmeric and black cumin both possess disease prevention properties like anti-diabetic, anti-hyperlipidemic, antioxidants and numerous others. Therapeutic effect of turmeric and black cumin was assessed by an efficacy study on streptozotocin induced diabetic rats. Rats were divided into 5 groups that are G0 consist of healthy rats, G1 consist of diabetic rats without giving any treatment, G2 involves diabetic rats received turmeric powder, G3 involves diabetic rats received black cumin powder and G4 consist of diabetic rats treated with combined mixture of turmeric powder and black powder. The objective of this study was to estimate the anti-diabetic role of turmeric and black cumin in rats. The result indicated that blood glucose level and serum lipid profile was greatly improved by combined mixture of turmeric and black cumin rather than the individual doses of turmeric and black cumin. Thus the result showed that turmeric and black cumin has potential to treat diabetes mellitus and related disorders.

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来源期刊

Pesquisa Agropecuaria Brasileira 农林科学-农业综合

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

9-18 weeks

期刊介绍： Pesquisa Agropecuária Brasileira – PAB – is issued monthly by Empresa Brasileira de Pesquisa Agropecuária – EMBRAPA, affiliated to Ministry of Agriculture, Livestock and Food Supply. PAB publishes original scientific-technological articles on Plant Physiology, Plant Pathology, Crop Science, Genetics, Soil Science, Food Technology and Animal Science. Its abbreviated title is Pesq. agropec. bras., and it should be used in bibliographies, footnotes, references and bibliographic strips.