{"title":"纳秒脉冲电磁场对线粒体膜电位的影响","authors":"X. Wenjun, Y. Xueling, C. Jingliang","doi":"10.1109/PLASMA.2016.7534132","DOIUrl":null,"url":null,"abstract":"In this paper, the effects of nanosecond pulsed electromagnetic field (NPEMF) on mitochondrial membrane potential were studied. The pulsed electromagnetic field was induced by a pulsed square wave with adjustable frequency of 0∼100Hz. The rise time was less than 10ns and the duration time was 100ns. The testing amplitude of NPEMF was from 0.10mT to 1.30mT, and the frequency was 5Hz, 10 Hz, 30 Hz, 50Hz respectively. It was applied on human prostate cancer cells (PC3) under 23 °C experiment temperature and 2 hours exposed time. When the frequency was 30Hz, the experimental results showed the mitochondrial membrane potential value decreased after irradiation compared to the control group. However the relationship between mitochondrial membrane potential and NPEMF is nonlinear. T he potential was smallest when the amplitude of NPEMF was 0.44mT. When the amplitude of NPEMF is constant, the mitochondrial membrane potential increased with the increase of frequency. The value of exposed group was larger than control group 2(23 C, no irradiation). It showed that the electromagnetic field could reduce the damage caused by low temperature.","PeriodicalId":6359,"journal":{"name":"2008 IEEE 35th International Conference on Plasma Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of nanosecond pulsed electromagnetic field on mitochondrial membrane potential\",\"authors\":\"X. Wenjun, Y. Xueling, C. Jingliang\",\"doi\":\"10.1109/PLASMA.2016.7534132\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper, the effects of nanosecond pulsed electromagnetic field (NPEMF) on mitochondrial membrane potential were studied. The pulsed electromagnetic field was induced by a pulsed square wave with adjustable frequency of 0∼100Hz. The rise time was less than 10ns and the duration time was 100ns. The testing amplitude of NPEMF was from 0.10mT to 1.30mT, and the frequency was 5Hz, 10 Hz, 30 Hz, 50Hz respectively. It was applied on human prostate cancer cells (PC3) under 23 °C experiment temperature and 2 hours exposed time. When the frequency was 30Hz, the experimental results showed the mitochondrial membrane potential value decreased after irradiation compared to the control group. However the relationship between mitochondrial membrane potential and NPEMF is nonlinear. T he potential was smallest when the amplitude of NPEMF was 0.44mT. When the amplitude of NPEMF is constant, the mitochondrial membrane potential increased with the increase of frequency. The value of exposed group was larger than control group 2(23 C, no irradiation). It showed that the electromagnetic field could reduce the damage caused by low temperature.\",\"PeriodicalId\":6359,\"journal\":{\"name\":\"2008 IEEE 35th International Conference on Plasma Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-06-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2008 IEEE 35th International Conference on Plasma Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/PLASMA.2016.7534132\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2008 IEEE 35th International Conference on Plasma Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/PLASMA.2016.7534132","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of nanosecond pulsed electromagnetic field on mitochondrial membrane potential
In this paper, the effects of nanosecond pulsed electromagnetic field (NPEMF) on mitochondrial membrane potential were studied. The pulsed electromagnetic field was induced by a pulsed square wave with adjustable frequency of 0∼100Hz. The rise time was less than 10ns and the duration time was 100ns. The testing amplitude of NPEMF was from 0.10mT to 1.30mT, and the frequency was 5Hz, 10 Hz, 30 Hz, 50Hz respectively. It was applied on human prostate cancer cells (PC3) under 23 °C experiment temperature and 2 hours exposed time. When the frequency was 30Hz, the experimental results showed the mitochondrial membrane potential value decreased after irradiation compared to the control group. However the relationship between mitochondrial membrane potential and NPEMF is nonlinear. T he potential was smallest when the amplitude of NPEMF was 0.44mT. When the amplitude of NPEMF is constant, the mitochondrial membrane potential increased with the increase of frequency. The value of exposed group was larger than control group 2(23 C, no irradiation). It showed that the electromagnetic field could reduce the damage caused by low temperature.
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