Ovopet治疗犬髋关节发育不良的疗效观察

A. Aguirre, E. Gil-Quintana, M. Fenaux, Núria Sanchez, C. Torre
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引用次数: 5

摘要

髋关节发育不良是一种广泛存在的疾病,可以影响所有年龄段的狗。髋关节发育不良是由髋关节半脱位引起的。这导致骨关节炎的发展,引起炎症和疼痛。在这种情况下,补充Ovopet®(蛋壳膜)的功效及其耐受性和安全性被评估。40只客户拥有的中型关节炎狗每天用安慰剂或Ovopet®治疗40天。每隔十天,对狗进行功能限制和关节活动(髋关节功能量表)、肌肉萎缩和活动范围(伸屈等级)的评估。研究人员还检查了狗的血液分析(炎症标志物),并在研究之前和结束时对髋关节间隙进行了超声检查。此外,还记录了业主在日常生活活动中的表现和评估的活力。基于这些观察,Ovopet®治疗组肌肉萎缩明显减少(p<0.05),活动范围明显改善。起跑跛行、行走跛行、跑玩阻力、小跳限制等指标均有显著改善(p<0.05)。自治疗第20天起,饲主评估的功能、积极行为描述和疼痛感觉参数均有显著改善(p<0.05)。根据记录数据,Ovopet®(15 mgKg-1dog)治疗提供了显著的改善,减少了狗的疼痛,从而改善了身体功能。关键词:Ovopet®,髋关节发育不良,犬,骨关节炎,饲料补充,蛋壳膜
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The efficacy of Ovopet in the treatment of hip dysplasia in dogs
Hip dysplasia is a widespread condition that can affect dogs of all ages. Hip dysplasia is caused by a subluxation in the hip joint. This leads to the development of osteoarthritis that causes inflammation and pain. At this sight, the efficacy of a supplement with Ovopet®, eggshell membrane, was evaluated together with its tolerability and safety. Forty client-owned medium sized arthritic dogs were treated daily for a period of 40 days with placebo or Ovopet®. Every ten days, the dogs were evaluated for functional limitation and joint mobility (hip functional scale), muscular atrophy and mobility range (extension-flexion rating). Dogs were also examined for blood analysis (inflammatory markers), and sonographies of the hip joint space were taken before and at the end of the study. Performances in daily life activities and vitality assessed by the owners were also recorded. Based on these observations, significant (p<0.05) reduction in muscular atrophy and improvement of mobility range was noted in Ovopet® treated group. Parameters such as as starting lameness, walking lameness, running and playing resistance and limitation to little jumps also experienced a significant (p<0.05) improvement. The parameters for function and positive behaviour description and pain sensation assessed by the owners showed a significant improvement (p<0.05) since day 20 of treatment. Based on recorded data, Ovopet® (15 mgKg-1dog) treatment provides a significant improvement, reducing the pain the dog has and therefore improving physical function. Key words: Ovopet®, hip dysplasia, dogs, osteoarthritis, feed supplement, eggshell membrane.
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