[锶-89治疗乳腺癌骨转移性神经性疼痛1例报告]。

Kaku igaku. The Japanese journal of nuclear medicine Pub Date : 2019-01-01 DOI:10.18893/kakuigaku.cr.1901

Y. Iizuka, M. Iizuka-Ohashi, S. Kawasaki, Ichiro Nakai, T. Mizowaki

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引用次数: 0

摘要

患者是一名47岁的女性，患有IV期乳腺癌和多发性骨转移。2013年至2018年，她接受了各种全身治疗(激素治疗和化疗)，并接受了乳房切除术;2018年初，她开始出现右髋关节骨转移性疼痛和左大腿背侧神经疼痛。这些症状逐渐加重，非甾体类抗炎镇痛药或麻醉性镇痛药对治疗这种疼痛无效。2018年4月进行锶-89 (89Sr)治疗。经89Sr治疗后疼痛立即缓解。病人的生活质量明显改善。直到2018年10月，由于原发疾病恶化，她在没有使用止痛药的情况下度过了余生。尽管人们认为放射治疗对神经性疼痛的效果不如骨转移性疼痛，但它应该被视为神经性疼痛患者的一种治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Effectiveness of Strontium-89 for Neuropathic Pain Caused by Bone Metastases from Breast Cancer: A Case Report].

The patient was a 47-year-old female with stage IV breast cancer and multiple bone metastases. She received various systemic therapies (hormone therapy and chemotherapy) and underwent mastectomy between 2013 and 2018; in the beginning of 2018, she started experiencing bone metastatic pain in the right hip joint and neural pain on the dorsal side of the left thigh. These symptoms worsened gradually, and nonsteroidal anti-inflammatory analgesics or narcotic analgesics were not effective for treating this pain. Strontium-89 (89Sr) treatment was administered in April 2018. The pain was relieved immediately after 89Sr treatment. The patient's quality of life improved markedly. She spent her remaining life without using analgesic drugs, until she died in October 2018 due to exacerbation of the original disease. Although radiotherapy is believed to be less effective for neuropathic pain than for bone metastatic pain, it should be considered as a treatment option in patients with neuropathic pain.

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来源期刊

Kaku igaku. The Japanese journal of nuclear medicine Medicine-Medicine (all)

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期刊介绍： The main scope of JSNM is the appropriate development of the application of radioactive substances and stable nuclides in medicine. Towards this scope, JSNM promotes the exchange of idea and information, and researches in nuclear medicine. JSNM are interested in the international collaboration for the development of nuclear medicine. Through the activities, JSNM contributes to the medicine, as well as humanity, not only in Japan but also in any countries over the world.