在活性棒的环境下,聚合物通过纳米孔进行易位

Hamidreza Khalilian, J. Sarabadani, T. Ala‐Nissila
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引用次数: 3

摘要

我们使用计算机模拟和等通量张力传播(IFTP)理论的结合来研究柔性线性聚合物通过纳米孔进入二维排斥性活性棒组成的环境的易位动力学。我们证明,杆的活性诱导聚合物的拥挤效应,导致一个时间依赖的净力,有利于转移到活性环境。将这种力结合到孔隙驱动易位的IFTP理论中,使我们能够详细描述易位动力学,并推导出平均易位时间的标度形式$\tilde{\tau} \sim \tilde{L}_{\textrm{r}}^{\nu} / \tilde{F}_{\textrm{SP}} $,其中$\tilde{L}_{\textrm{r}}$和$\tilde{F}_{\textrm{SP}}$分别是杆长和作用在杆上的自推进力,$\nu$是Flory指数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Polymer translocation through a nanopore assisted by an environment of active rods
We use a combination of computer simulations and iso-flux tension propagation (IFTP) theory to investigate translocation dynamics of a flexible linear polymer through a nanopore into an environment composed of repulsive active rods in 2D. We demonstrate that the rod activity induces a crowding effect on the polymer, leading to a time-dependent net force that facilitates translocation into the active environment. Incorporating this force into the IFTP theory for pore-driven translocation allows us to characterise translocation dynamics in detail and derive a scaling form for the average translocation time as $\tilde{\tau} \sim \tilde{L}_{\textrm{r}}^{\nu} / \tilde{F}_{\textrm{SP}} $, where $\tilde{L}_{\textrm{r}}$ and $\tilde{F}_{\textrm{SP}}$ are the rod length and self-propelling force acting on the rods, respectively, and $\nu$ is the Flory exponent.
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