催产素的多种作用

Sung Hye Kim, P. Bennett, V. Terzidou
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引用次数: 1

摘要

据报道,催产素/催产素受体(OT/OTR)系统影响人类的多种生理、行为和情绪过程。有广泛的研究关注他们在分娩,哺乳和行为中的作用。最近的研究调查了OT/OTR系统的新影响,包括炎症和mirna,以及它们的遗传多态性对分娩和分娩的影响。OT似乎对心肌细胞分化和心脏稳态也有很大影响,对肌肉维持和再生的年龄特异性调节也有很大影响。本文将对OT/OTR系统的作用进行综述,并对其新作用的研究进行综述,重点介绍其潜在的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diverse roles of oxytocin
The oxytocin/oxytocin receptor (OT/OTR) system has been reported to influence a variety of physiological, behavioural, and emotional processes in humans. There are a wide range of studies focusing on their role in parturition, lactation and behaviour. More recent studies have investigated the novel effects of OT/OTR system including inflammation and miRNAs, as well as the effect of their genetic polymorphisms on the onset of labour and parturition. OT also appears to have a great influence in cardiomyocyte differentiation and heart homeostasis, and an age-specific regulation of muscle maintenance and regeneration. This review will summarize the previously established role of OT/OTR system as well as the studies on their novel roles, and highlight the potential therapeutic approaches.
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