宫内生长受限的危险因素及其新生儿结局

T. Manandhar, B. Prashad, M. Pal
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引用次数: 20

摘要

IUGR是指胎儿未能达到其生长潜能。胎儿生长受多个层面的调控。除了母体疾病外,胎儿结构和染色体异常也是增加的因素。与IUGR相关的发病率可能对成人生活产生长期影响,容易导致许多慢性疾病的发展。目的:确定IUGR的各种危险因素及其新生儿结局。方法:该前瞻性研究在尼泊尔奇旺医学院妇产科进行,共纳入60例临床诊断的IUGR,研究时间为2年。结果:本组病例以26 ~ 30岁年龄组最多,占38.3%。IUGR常见于多gavida(75%)、农村(78.3%)、社会经济地位较低(63.3%)和体力劳动者(56.7%)。最常见的原因是母体(41.66%),其次是胎盘(16.66%)和胎儿(1.66%)。43.3% AFI正常的患者存在IUGR, 21.7%的患者存在严重的低水合胺<5 cm。多普勒测速显示2例脐带S/D异常(15.38%)。大多数患者(61.66%)需要剖腹产。36例(60%)新生儿出生体重在2.5 ~ 3.0 kg之间,83.01%新生儿IUGR不对称。15例(25%)新生儿有发病,但无死亡。结论:尽管IUGR仍然是一个挑战,但可以通过系统的方法和必要的管理来解决,特别是在超声检查和多普勒测速的帮助下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk Factors for Intrauterine Growth Restriction and Its Neonatal Outcome
Introduction: IUGR is the failure of the fetus to reach its growth potential. Fetal growth is regulated at multiple levels. Besides maternal disorder, fetal structural and chromosomal anomalies are the added factors. The morbidities associated with IUGR could have long term implications in adult life which predisposes in a development of a number of chronic diseases. Objectives: To identify the various risk factors for IUGR and its neonatal outcome. Methodology: It is a prospective study conducted in the Department of Obstetrics and Gynaecology, College of Medical Sciences, Chitwan, Nepal in which total of 60 cases of clinically diagnosed IUGR were enrolled during the study period of 2 years. Results: The study revealed maximum number of cases (38.3%) belonged to age between 26 to 30 years. IUGR was common in Multigavida (75%), rural area (78.3%), lower socioeconomic status (63.3%) and in manual worker (56.7%). Maternal (41.66%) was the commonest followed by Placental (16.66%) and Fetal (1.66%) causes. IUGR was observed in 43.3% with normal AFI and severe oligohydraminos <5 cm was observed in 21.7%. Doppler velocimetry showed abnormal umbilical S/D ratio in 2 (15.38%). Most of the patients (61.66%) required caesarean section. A total of 36 (60%) neonate had birth weight ranging between 2.5 to 3.0 kg and 83.01% had asymmetrical IUGR. Fifteen (25%) neonates had morbidity but there was no mortality. Conclusion: Even though IUGR continued to be a challenge and could be tackled with systemic approach and needful management, especially with the help of Ultrasonography and Doppler velocimetry.
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