胸部超声诊断COVID - 19肺炎的准确性

M. Ahmed, M. Mohamed
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引用次数: 0

摘要

理由:COVID - 19病毒感染是一种持续的灾难性全球大流行,发病率和死亡率都很高。大量感染COVID - 19病毒的人患COVID - 19肺炎的风险很高;病情恶化和病程延长的可能性越来越大。需要使用简单而便宜的图像进行COVID - 19肺炎的早期诊断、患者护理和隔离。始终建议减少医务人员和医务辅助人员接触COVID - 19患者的人数,高分辨率胸部CT (HRCT胸部)是诊断COVID - 19肺炎的金标准方法,但其费用昂贵,暴露风险增加;胸部超声检查可能是替代方法,但尚未得到证实。方法:在2020年5月至2020年10月期间,在阿苏特省门诊肺科门诊连续纳入评估COVID - 19肺炎的患者。对接受参与研究的患者进行胸部超声检查。HRCT胸部确诊COVID - 19肺炎在胸部超声检查后24小时内完成,胸部超声操作人员对HRCT胸部结果不知情;胸部超声检查由阿苏特大学医院胸科两名胸部超声专家进行。胸部超声检查采用Aloka和Fukuda超声设备的凸探头。胸部超声检查如发现单侧或双侧存在异常的多个垂直b线或实变点,心功能良好,则认为肺炎阳性,记录HRCT胸部结果。结果:纳入197例患者,平均年龄48±16.2岁,男性占52%,DM占10%,HTN占9%,住院5%,平均血氧饱和度为95±5%,HRCT胸部确诊肺炎152例,HRCT胸部正常45例。胸部超声诊断肺炎阳性128例,正常69例,与HRCT诊断COVID - 19肺炎有较好的相关性(R 0.690 p值<0.001)。胸部超声诊断covid - 19肺炎的敏感性为84.56%,特异性为95.83%,准确率为87.31%。102例患者在15天内随访成功,临床及超声检查均有改善。结论:胸部超声与胸部HRCT相比,特异性、敏感性和准确性高,患者暴露少,病毒传播少,是一种有前景的廉价评估COVID - 19肺炎的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Accuracy of Chest Ultrasonography in Diagnosis of COVID 19 Pneumonia
Rationale: COVID 19 virus infection is ongoing catastrophic worldwide pandemic with significant morbidity and mortality. Large numbers of persons that getting COVID19 virus infection at high risk of developing COVID 19 pneumonia;with increasing chance of worse and prolonged illness. Early diagnosis of COVID 19 pneumonia, patient care and isolation using simple less expensive image are wanted. Decreasing the numbers of medical and paramedical personnel exposure to COVID 19 patients is always recommended, High resolution CT Chest (HRCT chest) is the Gold standard method to diagnosis COVID 19 pneumonia;however it is expensive with increasing the exposure risk;chest ultrasonography may be alternative method, however still not confirmed. Methods: In consecutive patients referred to assess COVID 19 pneumonia in outpatient pulmonology clinic in Assiut Governorate;between May 2020 and October 2020. Chest ultrasonography was done for patients accepting to participate in the study. HRCT chest to confirm COVID 19 pneumonia were done within 24 hours of Chest ultrasonography exam, the chest ultrasonography operators were blind to HRCT chest results;chest ultrasonography were done by two chest consultants expert in chest ultrasonography at Chest Department of Assiut University Hospital . The chest ultrasonography was done using the convex probe of Aloka and Fukuda ultrasonography devices. The chest Ultrasonography considered positive for pneumonia if the examiners find presence of abnormal multiple vertical B-lines or presence of consolidations dots unilateral or bilateral with good cardiac function, HRCT chest result were recorded. Results: 197 patients are included in the study, with mean age 48 ±16.2 year , 52% male, 10% have DM, 9% have HTN, 5 % needed hospitalization, mean oxygen saturation were 95±5 percent, 152 patients confirmed COVID pneumonia with HRCT chest while 45 patients had normal HRCT chest , while chest ultrasonography positive finding for pneumonia in 128 patients while normal Chest ultrasonography 69patients ,Chest ultrasonography is having good association (R 0.690 p value <0.001)when correlated with HRCT to diagnose COVID 19 pneumonia. The sensitivity and specificity and accuracy of Chest ultrasonography in diagnosis of COVID19 pneumonia are 84.56% , 95.83% and 87.31% respectively when compared with HRCT chest.102 patients successfully followed within 15 days;all of them showing clinical and ultrasonographically improvement. Conclusion :Chest Ultrasonography is a promising cheap method for evaluation of COVID 19 pneumonia with high specificity , sensitivity and accuracy with less patients' exposure and virus spread when compared with HRCT chest .
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