从(-)-香樟醇到诺拉丹杂环杂化化合物

IF 0.5 Q4 CHEMISTRY, MULTIDISCIPLINARY

Chemistry Journal of Moldova Pub Date : 2022-12-01 DOI:10.19261/cjm.2022.958

A. Ciocarlan

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引用次数: 0

摘要

本文综述了从鼠尾草(Salvia sclarea L.)中提取的具有生物活性的天然二萜(-)-sclareol的化学成分。它主要用于工业，特别是用于合成芳香化合物和天然类似物。综述了在此基础上制备的含肼和硫代氨基脲片段或杂嗪、1,2,4-三唑、咔唑、1,3-噻唑、1,3,4-恶二唑、1,3,4-噻二唑等分子杂化化合物的合成、结构测定和生物活性研究进展。

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From (-)-sclareol to Norlabdane Heterocyclic Hybrid Compounds

This review relates to chemistry of the well-known biologically active natural labdane diterpenoid (-)-sclareol easily available from Clary sage (Salvia sclarea L.). It is mainly used in industry, especially for synthesis of fragrance compounds and natural analogs. The paper covers achievements on the synthesis, structure determination and biological activity of molecular hybrid compounds bearing hydrazide and thiosemicarbazone fragments or diazine, 1,2,4-triazole, carbazole, 1,3-thiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole units prepared based on it.

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来源期刊

Chemistry Journal of Moldova CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

0.90

自引率

20.00%

发文量

审稿时长

12 weeks

期刊介绍： "Chemistry Journal of Moldova. General, Industrial and Ecological Chemistry" seeks to publish experimental or theoretical research results of outstanding significance and timeliness in all fields of Chemistry, including Industrial and Ecological Chemistry. The main goal of this edition is strengthening the Chemical Society of Moldova, following development of research in Moldovan chemical institutions and promotion of their collaboration with international chemical community. Manuscripts are welcome from all countries.